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Related Concept Videos

Allergic Drug Reactions01:27

Allergic Drug Reactions

971
Allergic reactions related to drugs are hypersensitivity responses driven by the immune system and bear no connection to the drug's therapeutic action. While drugs in isolation do not trigger an immune response, they can interact with endogenous proteins to form antigens. These antigens stimulate lymphocytes to produce antibodies. IgE-type antibodies attach themselves to mast cells. Upon subsequent exposure to the same stimulus, the antigen-antibody interaction is initiated, unleashing...
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Allergic Reactions02:06

Allergic Reactions

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Overview
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Radiological Investigation III: Pulmonary Angiogram and PET Scan01:13

Radiological Investigation III: Pulmonary Angiogram and PET Scan

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Radiological investigations are paramount in the diagnosis and management of various pulmonary diseases. Two essential investigations are the Pulmonary Angiogram and the Positron Emission Tomography (PET) Scan.
Pulmonary Angiogram
A Pulmonary Angiogram is an invasive procedure involving injecting a contrast medium through a catheter threaded into the pulmonary artery or the right side of the heart to visualize the pulmonary vasculature. Computed Tomography (CT) scans have mainly replaced this...
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Pulmonary Tuberculosis V01:28

Pulmonary Tuberculosis V

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Medical management of tuberculosis (TB) patients involves a comprehensive approach that includes diagnosis, treatment, and monitoring. The specific strategies can vary depending on the type of tuberculosis (latent or active), the patient's overall health status, and other considerations.
Latent tuberculosis infection occurs when TB bacteria are present in a person's body, but are not causing illness or symptoms. It is not contagious, and preventive treatment is crucial to avoid the...
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Imaging Studies for Cardiovascular System V: CT01:28

Imaging Studies for Cardiovascular System V: CT

66
Cardiac computed tomography (CT) scanning is an advanced cardiac imaging technique that utilizes CT technology, with or without intravenous (IV) contrast, to produce accurate cross-sectional virtual slices of specific areas of the heart, coronary circulation, and major blood vessels such as the aorta, pulmonary veins, and arteries. The computer processes these slices to generate three-dimensional images. Multidetector CT (MDCT) is a rapid form of CT scanning that captures multiple slices...
66
Precipitation Gravimetry01:03

Precipitation Gravimetry

7.3K
Precipitation gravimetry is based on converting an analyte into a sparingly soluble precipitate, which is separated by filtration and weighed. An ideal precipitate should be pure, insoluble, of known composition, and easily filtered from the reaction mixture.
In determining nickel by gravimetric analysis, a precipitant of ethanolic dimethylglyoxime is added to a hot nickel salt solution. This is quickly followed by the dropwise addition of dilute ammonia solution until precipitation occurs. A...
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Related Experiment Video

Updated: Sep 8, 2025

Use of Electromagnetic Navigational Transthoracic Needle Aspiration E-TTNA for Sampling of Lung Nodules
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Use of Electromagnetic Navigational Transthoracic Needle Aspiration E-TTNA for Sampling of Lung Nodules

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TAVR Patients With Nickel Allergy.

Stefan Milutinovic1, Katarzyna Karpinska-Leydier1, Richard A Chazal2

  • 1Florida State University College of Medicine Internal Medicine Residency Program at Lee Health, Cape Coral, Florida, USA.

JACC. Case Reports
|September 5, 2025
PubMed
Summary
This summary is machine-generated.

Transcatheter aortic valve replacement (TAVR) is safe for patients with nickel allergy. Routine allergy testing before TAVR may not be necessary, as no severe reactions were observed in this patient series.

Area of Science:

  • Cardiology
  • Allergy and Immunology
  • Medical Devices

Background:

  • Severe aortic stenosis often necessitates transcatheter aortic valve replacement (TAVR).
Keywords:
nickel allergytranscatheter aortic valve replacement (TAVR)

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  • Metallic valve frames in TAVR devices raise safety concerns for patients with nickel allergy.
  • Nickel hypersensitivity is a prevalent concern in the general population.