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Related Concept Videos

Peroxisomes01:30

Peroxisomes

Peroxisomes and mitochondria are two important oxygen-utilizing organelles in eukaryotic cells. Mitochondria carry out cellular respiration—the process that converts energy from food into ATP. Peroxisomes carry out a variety of functions, primarily breaking down different substances, such as fatty acids.The peroxisome is a single membrane-bound cellular organelle that can perform several different functions, including lipid metabolism and chemical detoxification. The enzymes within peroxisomes...
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Enzyme-linked receptors are proteins that act as both receptor and enzyme, activating multiple intracellular signals. This is a large group of receptors that include the receptor tyrosine kinase (RTK) family. Many growth factors and hormones bind to and activate the RTKs.
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MXene-Based Peroxidase-Like Nanozymes: Interfacial Effects for Biomedical Applications.

Tianye Zhang1, Mengtian Lu1, Xin Lin1

  • 1College of Chemistry, Chemical Engineering and Resource Utilization, Northeast Forestry University, Harbin, 150040, P. R. China.

Chemical Record (New York, N.Y.)
|September 6, 2025
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Summary

MXene-based peroxidase nanozymes show promise for biomedical uses. Modulating their interfaces with external stimuli enhances catalytic activity for applications in biosensing and disease therapy.

Keywords:
MXenesinterfacial effectsnanomaterialsnanozymesperoxidase

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Area of Science:

  • Biomaterials Science
  • Nanotechnology
  • Catalysis

Background:

  • MXene-based peroxidase (POD)-like nanozymes offer unique 2D structures, tunable catalysis, and interfacial effects for biomedical applications.
  • Understanding and manipulating interfacial effects is key to enhancing their performance.

Purpose of the Study:

  • To review recent advancements in MXene-POD nanozyme design.
  • To explore strategies for modulating interfacial effects using external stimuli.
  • To summarize applications in biosensing, antimicrobial agents, and disease therapy.

Main Methods:

  • Focus on interfacial effects modulation via external stimuli (near-infrared light, pH, magnetic fields).
  • Analysis of strategies to enhance electron density distribution and catalytic efficiency.
  • Review of applications in biosensing, antimicrobial agents, and disease therapy.

Main Results:

  • External stimuli effectively modulate interfacial effects, enhancing MXene-POD nanozyme catalytic efficiency.
  • Tailored MXene-POD nanozymes show significant potential in biosensing, antimicrobial applications, and disease treatment.
  • Specific strategies influence the efficacy across diverse biomedical applications.

Conclusions:

  • MXene-POD nanozymes are promising for biomedical applications.
  • Interfacial engineering is crucial for optimizing their performance.
  • Further research is needed to address current challenges and unlock full potential.