MXene-Based Peroxidase-Like Nanozymes: Interfacial Effects for Biomedical Applications

Area of Science:

• Biomaterials Science
• Nanotechnology
• Catalysis

Background:

• MXene-based peroxidase (POD)-like nanozymes offer unique 2D structures, tunable catalysis, and interfacial effects for biomedical applications.
• Understanding and manipulating interfacial effects is key to enhancing their performance.

Purpose of the Study:

• To review recent advancements in MXene-POD nanozyme design.
• To explore strategies for modulating interfacial effects using external stimuli.
• To summarize applications in biosensing, antimicrobial agents, and disease therapy.

Main Methods:

• Focus on interfacial effects modulation via external stimuli (near-infrared light, pH, magnetic fields).
• Analysis of strategies to enhance electron density distribution and catalytic efficiency.
• Review of applications in biosensing, antimicrobial agents, and disease therapy.

Main Results:

• External stimuli effectively modulate interfacial effects, enhancing MXene-POD nanozyme catalytic efficiency.
• Tailored MXene-POD nanozymes show significant potential in biosensing, antimicrobial applications, and disease treatment.
• Specific strategies influence the efficacy across diverse biomedical applications.

Conclusions:

• MXene-POD nanozymes are promising for biomedical applications.
• Interfacial engineering is crucial for optimizing their performance.
• Further research is needed to address current challenges and unlock full potential.