Related Experiment Video
Updated: Sep 8, 2025
Rapid Fractionation and Isolation of Whole Blood Components in Samples Obtained from a Community-based Setting
Published on: November 30, 2015
If you build it, they will come - Implementation of a prehospital whole blood program
R B Fransman1, C H Meyer1, J Nguyen2
1Emory University School of Medicine, USA; Grady Health System, USA.
Introduction:
We sought to develop, implement and evaluate an urban prehospital whole blood (PH-WB) program.
Methods:
Using retrospective heat map data, Quick Response Vehicles (QRVs) carrying PH-WB were strategically placed throughout the city and dispatched using dynamic deployment. Patient inclusion criteria were age ≥15 years, traumatic mechanism, and SBP ≤90 mmHg. Prospective data were collected between 3/21-6/21/2025.
Results:
375 patients were transfused 588 units of PH-WB, with 55 % receiving >1 unit. With transfusion, the average SBP increased by 28 mmHg and pulse decreased by 19 bpm from field to ED arrival. The overall survival at 24-h and 30-days was 83 % and 80.8 %, respectively.
Conclusion:
This study demonstrates the successful implementation of large-scale PH-WB program utilizing creative strategies to cover a large catchment zone with limited resources. Preliminary results document safe delivery of PH-WB, minimal variation in pre-hospital scene times, 0 % expiration rate of whole-blood in the field and high compliance with protocols.
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