Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Brain Imaging01:14

Brain Imaging

308
Brain imaging technologies provide critical insights into both the structure and function of the human brain, enabling medical professionals and researchers to diagnose, study, and treat neurological disorders or psychiatric disorders more effectively.
These technologies include computerized axial tomography (CAT or CT scans), positron-emission tomography (PET scans),  magnetic resonance imaging (MRI),  functional magnetic resonance imaging (fMRI), and Transcranial Magnetic...
308

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Disentangling shared and unique effects of parenting on psychopathology: Evidence from two prospective, genetically sensitive cohort studies.

JCPP advances·2026
Same author

A blended genome and exome sequencing method captures genetic variation in an unbiased and cost-effective manner.

Nature genetics·2026
Same author

Brain Aging in Specific Phobia: An ENIGMA-Anxiety Mega-Analysis.

Human brain mapping·2026
Same author

Shared and specific associations of amygdala nuclei volumes with PTSD symptom domains and childhood trauma: An ENIGMA-PGC PTSD mega-analysis.

Molecular psychiatry·2026
Same author

Genome-wide association studies of infant and toddler temperament in European and multi-ancestry populations.

Nature human behaviour·2026
Same author

How does maternal "belief in a dangerous world" affect maternal and child depressive symptoms during times of crisis?

Journal of affective disorders reports·2026

Related Experiment Video

Updated: Sep 8, 2025

Optimized Analysis of DNA Methylation and Gene Expression from Small, Anatomically-defined Areas of the Brain
13:11

Optimized Analysis of DNA Methylation and Gene Expression from Small, Anatomically-defined Areas of the Brain

Published on: July 12, 2012

18.9K

Consortium profile: the methylation, imaging and NeuroDevelopment (MIND) consortium.

Isabel K Schuurmans1, Rosa H Mulder1, Vilte Baltramonaityte2

  • 1Department of Child and Adolescent Psychiatry and Psychology, Erasmus MC University Medical Center Rotterdam, Rotterdam, the Netherlands.

Molecular Psychiatry
|September 6, 2025
PubMed
Summary

The Methylation, Imaging and NeuroDevelopment (MIND) Consortium studies how DNA methylation relates to brain development. This large, collaborative effort uses longitudinal data to understand epigenetic influences on neurodevelopmental and psychiatric phenotypes.

More Related Videos

Molecular Imaging of Human Brain Organoids Using Mass Spectrometry
08:04

Molecular Imaging of Human Brain Organoids Using Mass Spectrometry

Published on: September 27, 2024

858
Profiling Maternal Behavior Responses During Whole-Brain Imaging
07:12

Profiling Maternal Behavior Responses During Whole-Brain Imaging

Published on: January 24, 2025

1.1K

Related Experiment Videos

Last Updated: Sep 8, 2025

Optimized Analysis of DNA Methylation and Gene Expression from Small, Anatomically-defined Areas of the Brain
13:11

Optimized Analysis of DNA Methylation and Gene Expression from Small, Anatomically-defined Areas of the Brain

Published on: July 12, 2012

18.9K
Molecular Imaging of Human Brain Organoids Using Mass Spectrometry
08:04

Molecular Imaging of Human Brain Organoids Using Mass Spectrometry

Published on: September 27, 2024

858
Profiling Maternal Behavior Responses During Whole-Brain Imaging
07:12

Profiling Maternal Behavior Responses During Whole-Brain Imaging

Published on: January 24, 2025

1.1K

Area of Science:

  • Neuroscience
  • Genetics
  • Developmental Biology

Background:

  • Epigenetic processes like DNA methylation are key to gene-environment interactions affecting brain phenotypes.
  • Understanding peripheral epigenetic patterns' relation to individual brain differences is limited, especially in developmental contexts.
  • Existing research primarily uses cross-sectional adult data, lacking a developmental perspective.

Purpose of the Study:

  • Establish the Methylation, Imaging and NeuroDevelopment (MIND) Consortium to focus on developmental Neuroimaging Epigenetics.
  • Promote collaborative, powered developmental research through multi-cohort analyses.
  • Advance understanding of DNA methylation-brain dynamics across development using longitudinal pediatric data.

Main Methods:

  • Integrate 16 international cohorts with longitudinal DNA methylation and neuroimaging data.
  • Collect repeated measures of DNA methylation (blood, buccal, saliva) and MRI across development (birth to adulthood).
  • Employ shared pipelines and open science practices for scientific rigor.

Main Results:

  • MIND integrates data from N=12,877 (DNAm), N=10,899 (neuroimaging), and N=6074 (combined) participants.
  • Data spans up to five time points over 21 years, capturing developmental trajectories.
  • Triangulates associations across multiple time points and study types to reveal dynamic relationships.

Conclusions:

  • MIND provides a unique, large-scale developmental dataset for Neuroimaging Epigenetics.
  • The consortium aims to generate novel insights into peripheral DNA methylation and brain relationships.
  • Findings will elucidate epigenetic contributions to neurodevelopmental and psychiatric phenotypes.