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Updated: Jan 18, 2026

A Kinetic Fluorescence-based Ca2+ Mobilization Assay to Identify G Protein-coupled Receptor Agonists, Antagonists, and Allosteric Modulators
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A Kinetic Fluorescence-based Ca2+ Mobilization Assay to Identify G Protein-coupled Receptor Agonists, Antagonists, and Allosteric Modulators

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Physiological functions and structural features of Gα12/13 proteins

Sabriye Aydoğdu1, Anna Pepanian1, Dhruv C Rathod1

  • 1Pharmaceutical Biochemistry and Bioanalytics, Pharmaceutical Institute, University of Bonn, Bonn 53121, Germany.

Biomedicine & Pharmacotherapy = Biomedecine & Pharmacotherapie
|September 7, 2025
PubMed

Keywords:
G protein structureGPCRsGα12/13Heterotrimeric G proteinsSignaling

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