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Methods used in early value assessments for nice: a scoping review.

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This study reviewed early value assessments (EVAs) from NICE, finding inconsistencies in reporting methods. Future EVAs should improve transparency and methodological innovation for better health technology evaluations.

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Area of Science:

  • Health economics
  • Health technology assessment
  • Health services research

Background:

  • The National Institute for Health and Care Excellence (NICE) in England implemented early value assessments (EVAs) to expedite access to innovative health technologies.
  • EVAs aim to address unmet medical needs and align with the National Health Service's Long Term Plan.
  • A gap exists in published literature detailing the methodological commonalities and differences across EVA Assessment Reports.

Purpose of the Study:

  • To conduct a scoping review of completed EVAs published by NICE.
  • To identify and analyze the methods employed in the Assessment Reports of early value assessments.
  • To highlight variations and consistencies in methodologies used within EVAs.

Main Methods:

  • A rapid scoping review was performed on all completed EVAs available on the NICE website up to July 23, 2024.
  • Screening and data extraction were conducted by two independent reviewers using a piloted form.
  • Data were synthesized and presented using narrative summaries, graphical, or tabular formats.

Main Results:

  • Seventeen EVA Reports from sixteen EVAs were included.
  • Methodological reporting varied, with some reports omitting details on reviewer numbers and data extraction.
  • Planned analytical approaches included meta-analyses (5), narrative syntheses (9), and narrative summaries (7).
  • Eleven conceptual decision models were used, with economic evaluations comprising cost-utility analyses (5), cost-effectiveness analyses (4), and cost-consequence analyses (3).

Conclusions:

  • Enhanced transparency in reporting methods is recommended for future EVA Reports.
  • EVAs present opportunities for adopting novel methodological approaches.
  • Increased flexibility in communication between EVA authors, stakeholders (patients, clinicians, companies), and NICE is encouraged.