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Advancing Wound Care With 3-D Imaging: Clinical Applications, Performance and Future Directions.
Adriano Antonio Mehl1, Nicole Abdullah2, Paula Karina Hembecker3
1Visiting Researcher at the Graduate Program in Health Technology (PPGTS) at Pontifical Catholic University of Paraná (PUC-PR), Paraná, Brazil.
Summary
Three-dimensional (3D) wound assessment technologies offer precise wound measurement and monitoring for chronic wounds. However, further validation and integration into predictive models are needed to fully realize their clinical potential in wound care.
Area of Science:
- Biomedical Engineering
- Wound Care Technology
- Medical Imaging
Background:
- Chronic wounds represent a significant global health burden, necessitating accurate monitoring for effective healing.
- Traditional 2D wound assessment methods lack the volumetric data crucial for comprehensive analysis.
- Emerging 3D imaging technologies promise enhanced precision but require clinical validation and assessment of prognostic utility.
Purpose of the Study:
- To systematically review and synthesize evidence on the clinical application of 3D wound assessment technologies in adults with chronic wounds.
- To evaluate the predictive potential of these 3D technologies for wound healing outcomes.
- To map the landscape of current 3D wound assessment tools and their reported performance.
Main Methods:
- A comprehensive scoping review was conducted using five major electronic databases (MEDLINE, EMBASE, Web of Science, CINAHL, IEEE Xplore).
- Peer-reviewed studies published between 2014 and 2024 evaluating 3D wound assessment technologies were included.
- Data extraction and narrative synthesis were performed by two independent reviewers, focusing on methodological quality and standardization.
Main Results:
- Eleven studies involving 734 wounds and 307 patients were included, evaluating technologies like OCT, structured-light scanners, stereophotogrammetry, and smartphone-based systems.
- Most 3D platforms showed high reproducibility for surface area and moderate accuracy for depth and volume.
- Significant methodological heterogeneity and lack of standardized validation protocols limited cross-platform comparisons, with no studies integrating volumetric data into predictive models.
Conclusions:
- 3D wound assessment technologies demonstrate substantial potential for improving the precision of wound measurement, documentation, and non-invasive monitoring.
- Standardized validation frameworks are essential for robustly evaluating these technologies.
- Integrating volumetric data from 3D assessments into predictive healing models is crucial for advancing precision wound care.

