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ALK-negative retroperitoneal inflammatory myofibroblastic tumor treated conservatively: case report
Fu-Xiang Lin1,2, Wei Wei1,2, Yi Yu1,2
1Department of Urology, The Eighth Clinical Medical College of Guangzhou University of Chinese Medicine, No. 6 of Qinren Road, Foshan 528000, Guangdong, People's Republic of China.
None:
A 55-year-old female presented with left flank pain and ureteral obstruction. Imaging revealed a retroperitoneal mass suspicious for malignancy. Histopathology confirmed an inflammatory myofibroblastic tumor (IMT; anaplastic lymphoma kinase [ALK]-negative, mouse double minute 2 homolog-positive). Due to vascular encasement prohibiting safe resection, cystoscopic ureteral stenting was performed followed by 12 months of prednisone and celecoxib therapy. Serial imaging showed progressive regression, with near-resolution at 36 months. This demonstrates successful medical management of unresectable ALK-negative retroperitoneal IMT.