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Updated: Jan 18, 2026

Developing a Rat Model for Bipolar Disorder
Published on: May 2, 2025
Community re-entry program on global functioning and medication adherence among bipolar affective disorder patients-
Jaishri1, Sreevani Rentala2, Preethy Kathiresan3
1Department of Mental Health Nursing, College of Nursing, AIIMS, Jodhpur, Rajasthan, India.
The community re-entry program (CREP) significantly improved medication adherence in bipolar disorder patients. While CREP showed no significant effect on global functioning, it is valuable for managing bipolar disorder and preventing symptom recurrence.
Area of Science:
- Psychiatry
- Mental Health Research
- Clinical Psychology
Background:
- Community re-entry programs (CREP) aim to equip patients with skills for independent living post-inpatient care.
- Bipolar affective disorder requires effective management strategies to prevent symptom recurrence and improve patient outcomes.
Purpose of the Study:
- To quantitatively explore the effectiveness of a community re-entry program on global functioning and medication adherence in bipolar affective disorder patients.
- To assess the impact of CREP on patient recovery and long-term management of bipolar disorder.
Main Methods:
- A randomized controlled trial (N=50) adhering to CONSORT 2010 guidelines was conducted.
- Participants were assessed using the World Health Organisation Disability Assessment Schedule 2.0 and Medication Adherence Rating Scale.
- The intervention group received 8 daily 45-minute sessions of the community re-entry program, with assessments at baseline, post-intervention, and 1-month follow-up.
Main Results:
- The community re-entry program demonstrated a significant time effect and group effect on medication adherence, with a large interaction effect.
- Global functioning showed a significant time effect with a large effect size, but no significant group or interaction effect was observed.
- Post-intervention analysis indicated significant improvements in medication adherence for the intervention group compared to the control group.
Conclusions:
- The community re-entry program (CREP) is effective in enhancing medication adherence among patients with bipolar affective disorder.
- Improved medication adherence facilitated by CREP contributes to the treatment and prevention of symptom recurrence in bipolar disorder.
- Further research may explore CREP's impact on other aspects of functioning in bipolar disorder patients.
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