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Updated: Jan 18, 2026

Characterization of In Vitro Differentiation of Human Primary Keratinocytes by RNA-Seq Analysis
Published on: May 16, 2020
Keratosis Pilaris Unveiled: Insights into its Origin, Management Strategies and Research Frontiers
Komalpreet Kaur1, Amrinder Kaur1, Vandna Kalsi2
1From the Department of Ayurveda, School of Pharmaceutical Sciences, Lovely Professional University, Jalandhar, Punjab, India.
Abstract:
Follicular hyperkeratosis is frequently known as keratosis pilaris (KP). Small, folliculocentric keratotic papules with possible erythematous borders are its defining features. It is a common, asymptomatic skin disorder. The tiny papules give the skin a stippled, gooseflesh-like appearance. The disorder most frequently affects the exterior portions of the upper arms, upper legs and buttocks. It is caused by prolonged exposure to the sun and people suffering from dry skin. The consequences of KP disease are mainly triggered by dryness and rough skin, which results in bumpy skin, redness, irritation, itching and hyperpigmentation. It can affect persons of any age, but it is more prevalent in children and teenagers. While the classic KP is known, the other variants are also there which have particular effects on the different parts of the body. To alleviate symptoms, apply moisturizers, exfoliates and topical treatments containing urea, lactic acid or salicylic acid. This critical issue must be addressed; there have been very few clinical studies, and this study will assist researchers in carrying out more clinical trials and studies on KP disorder. Being aware of KP is a very important point while it is not entirely preventable, using regular moisturizer, keeping gentle exfoliation and the use of light cleansers can all help to manage and reduce its appearance. There are a few current therapies used to treat the disease, including laser and blue light treatments, and photodynamic therapies.

