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Related Concept Videos

Hepatic Encephalopathy01:29

Hepatic Encephalopathy

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DefinitionHepatic encephalopathy is a reversible neurologic syndrome that results from advanced liver dysfunction or portosystemic shunting. It leads to disturbances in cognition, behavior, and motor function due to the brain’s exposure to gut-derived toxins that the liver fails to detoxify.EtiologyThis condition develops either in the setting of acute fulminant hepatitis or progressively during chronic liver disease, such as cirrhosis and portal hypertension. Portosystemic...
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Microdialysis of Excitatory Amino Acids During EEG Recordings in Freely Moving Rats
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Delayed Posthypoxic Leukoencephalopathy in a Catatonic-Appearing Patient: A Case Report.

Meredith Bentley1, Jordan Gaal1, Janice Hostetter1

  • 1Department of Psychiatry and Behavioral Medicine, Marshall University Joan C. Edwards School of Medicine, Huntington, West Virginia, USA.

Case Reports in Psychiatry
|September 8, 2025
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Summary

Delayed posthypoxic leukoencephalopathy (DPHL) is a rare condition mimicking other neurological disorders. This case highlights DPHL

Area of Science:

  • Neurology
  • Neuroimaging
  • Toxicology

Background:

  • Delayed posthypoxic leukoencephalopathy (DPHL) is a rare neurological disorder.

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  • It can be misdiagnosed due to overlapping symptoms with conditions like catatonia.
  • Causes include anoxia from carbon monoxide poisoning, drug overdose, or cardiac arrest.