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Subgaleal Hematoma in a Female With Normal Coagulation Tests
Sajjad Ataei-Azimi1, Mettine H A Bos2, Hossein Rahimi1
1Hematology and Oncology Section, Department of Internal Medicine, Ghaem Hospital, Mashhad University of Medical Sciences, Mashhad, Iran.
Case Reports in Hematology
|September 8, 2025
Summary
Factor XIII (FXIII) deficiency causes bleeding disorders, often missed by standard clot solubility tests. Quantitative FXIII activity assays are crucial for accurate diagnosis of this rare coagulopathy.
Area of Science:
- Hematology
- Coagulation Disorders
Background:
- Factor XIII (FXIII) deficiency is a rare coagulopathy affecting hemostasis by impairing fibrin clot stabilization.
- Clinical presentation includes diverse hemorrhagic manifestations, often with normal primary hemostasis screening tests.
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