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Flexible, Transparent, and Microfluidic-Compatible Wafer-Scale Metamaterial Sheets for Dual SEF and SERS Sensing
Xiujia Wu1,2, Shan Ding1,2, Jia Sun1,2
1Department of Micro/Nano Electronics, School of Electronic Information and Electrical Engineering, Shanghai Jiao Tong University, Shanghai 200240, China.
ACS Applied Materials & Interfaces
|September 8, 2025
Summary
This study presents a novel plasmonic metamaterial sheet integrating surface-enhanced fluorescence (SEF) and surface-enhanced Raman spectroscopy (SERS) for enhanced molecular detection. The flexible, transparent platform offers high sensitivity and specificity for applications like microplastic detection.
Area of Science:
- Plasmonics
- Spectroscopy
- Materials Science
Background:
- Surface-enhanced fluorescence (SEF) and surface-enhanced Raman spectroscopy (SERS) are powerful techniques for molecular analysis.
- Current limitations include challenges in achieving high SEF and SERS simultaneously, restricted spectral coverage, and poor scalability.
Purpose of the Study:
- To develop a flexible, transparent, and scalable plasmonic metamaterial sheet integrating both SEF and SERS.
- To overcome the limitations of existing plasmon-enhanced spectroscopy (PES) platforms.
Main Methods:
- Fabrication of a wafer-scale plasmonic metamaterial sheet (PLAMS) supporting broadband localized surface plasmon resonances (LSPRs).
- Integration of SEF and SERS capabilities onto the PLAMS without dielectric spacers.
- Demonstration of dual SEF and SERS sensing using polystyrene microplastics.
Main Results:
- Achieved simultaneous high SEF (∼209) and SERS (∼1.17 × 106) enhancements with high signal uniformity.
- Realized broadband LSPRs (∼400–1000 nm) for extended fluorophore compatibility.
- Demonstrated rapid screening via SEF and ultrasensitive, specific characterization via SERS, including single-particle detection.
Conclusions:
- The developed PLAMS is a flexible, transparent, and scalable platform for dual SEF and SERS sensing.
- This integrated approach overcomes key limitations in PES, enabling rapid prototyping and pragmatic applications.
- The platform shows significant promise for advancing plasmon-enhanced spectroscopy for various sensing applications.
