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Long-term outcomes of corneal patch grafts
Muzaffer Talha Albayrak1, Burcu Kasım2, Emine Çiloğlu3
1Department of Ophthalmology, Kayseri State Hospital, Kayseri, Turkey. mtalhalbayrak@gmail.com.
Cell and Tissue Banking
|September 8, 2025
Summary
Corneal patch grafting (CPG) effectively restores eye anatomy in most cases. Younger age, peripheral graft placement, and smaller graft size improve functional outcomes after CPG.
Area of Science:
- Ophthalmology
- Corneal Surgery
- Regenerative Medicine
Background:
- Corneal patch grafting (CPG) is a surgical technique used to repair corneal defects.
- Evaluating long-term outcomes and identifying prognostic factors for CPG is crucial for patient management.
Purpose of the Study:
- To assess the long-term anatomical and functional success rates of corneal patch grafting.
- To determine factors influencing the prognosis of corneal patch grafting outcomes.
Main Methods:
- Retrospective study of 35 patients who underwent CPG between April 2016 and September 2022.
- Data collected included patient demographics, graft characteristics, surgical procedures, and visual acuity outcomes.
- Statistical analysis was performed to identify prognostic factors for anatomical and functional success.
Main Results:
- Anatomical success was achieved in 82.9% of cases, with functional success in 45.7%.
- Younger age, peripheral graft location, and smaller graft diameter were favorable prognostic factors for functional recovery.
- Postoperative best-corrected visual acuity significantly improved (p < 0.001).
Conclusions:
- Corneal patch grafting is highly effective for anatomical restoration and offers acceptable functional outcomes in select patients.
- Key prognostic factors for successful functional recovery include younger patient age, peripheral graft placement, and smaller graft size.
