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Leveraging Multi-Text Joint Prompts in SAM for Robust Medical Image Segmentation.

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    IEEE Journal of Biomedical and Health Informatics
    |September 8, 2025
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    This study introduces a new framework using the Segment Anything Model (SAM) with text prompts for medical image segmentation. The approach improves accuracy and usability over standard SAM methods.

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    Area of Science:

    • Artificial Intelligence
    • Medical Imaging
    • Computer Vision

    Background:

    • The Segment Anything Model (SAM) shows promise for medical image segmentation.
    • Text prompts offer a more efficient alternative to geometric prompts for SAM in medicine.
    • Existing methods for text-prompted SAM in medicine are underexplored.

    Purpose of the Study:

    • To propose a novel SAM-based framework utilizing vision-language models for text-prompted medical image segmentation.
    • To address the challenges of semantic ambiguity and information redundancy in clinical text descriptions.
    • To enhance the performance and usability of SAM for medical applications through optimized text prompts.

    Main Methods:

    • Integrated a pre-trained vision-language model (e.g., CLIP) to generate referring prompts for SAM.
    • Developed a text decomposition-recomposition strategy to parse and recombine clinical narratives into effective semantic units.
    • Employed a cross-attention module to refine feature focus based on optimized text descriptions.

    Main Results:

    • The proposed SAM-based framework demonstrated improved performance compared to native SAM with geometric prompts.
    • The text decomposition-recomposition strategy effectively handled complex medical text descriptions.
    • Experiments on multiple datasets validated the enhanced usability and accuracy of the method.

    Conclusions:

    • The developed framework offers a viable and effective approach for text-prompted medical image segmentation using SAM.
    • Optimizing text prompts through decomposition and recomposition is crucial for leveraging vision-language models with SAM in clinical settings.
    • This method presents a significant advancement in the application of foundation models for medical image analysis.