Negative Pressure Wound Therapy: An Adjunct in Reconstructing Large Periocular Defects From Necrotizing Fasciitis
Michael T Kryshtalskyj1, Carson D Schell2, Brett Byers1
1Department of Surgery, Cumming School of Medicine, University of Calgary, Calgary, Alberta.
The Journal of Craniofacial Surgery
|September 8, 2025
Summary
Negative pressure wound therapy (NPWT) effectively reconstructs large periocular defects from necrotizing fasciitis (NF). This technique, combined with other methods, achieved excellent functional and aesthetic outcomes in three patients.
Area of Science:
- Ophthalmology
- Plastic Surgery
- Wound Healing
Background:
- Necrotizing fasciitis (NF) is a severe soft tissue infection.
- Periocular NF presents significant challenges for reconstruction.
- Early and effective management is crucial for preserving function and aesthetics.
Purpose of the Study:
- To demonstrate the utility of negative pressure wound therapy (NPWT) in managing large periocular tissue defects.
- To showcase NPWT combined with other reconstructive techniques for periocular NF.
- To evaluate the safety and efficacy of this approach.
Main Methods:
- Case series describing three patients with periocular NF.
- Surgical debridement followed by NPWT application.
- Subsequent reconstruction using skin grafts, muscle flaps, and biodegradable matrices.
Main Results:
- NPWT promoted wound granulation and contraction, facilitating reconstruction.
- All patients achieved excellent functional and aesthetic outcomes within 6-9 months.
- No ophthalmic complications were observed post-treatment.
Conclusions:
- NPWT is a safe and effective adjunct in the complex reconstruction of periocular defects caused by NF.
- The described technique offers a viable solution for challenging periocular tissue loss.
- Successful outcomes highlight the importance of multidisciplinary management.
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