Related Experiment Video
Updated: Jan 18, 2026

Multimodality Diagnosis of Mesenteric Ischemia
Published on: July 21, 2023
Management and outcomes of chronic mesenteric ischemia in older adults: A comprehensive review
Yashashwini Sudina1, Hind Anan1, Joelle Daher2
1UPMC Presbyterian Hospital, 200 Lothrop Street, South Tower, Third Floor, Pittsburgh, PA 15213.
Insights
Diagnosing and treating chronic mesenteric ischemia (CMI) in older adults is challenging due to aging factors and comorbidities. This review highlights age-specific strategies for better CMI patient outcomes.
Area of Science:
- Vascular Surgery
- Geriatric Medicine
Background:
- Chronic mesenteric ischemia (CMI) is increasingly prevalent in older adults.
- Diagnosis and treatment are complicated by comorbidities and age-related physiological changes.
- Existing guidelines lack age-specific considerations for CMI management.
Purpose of the Study:
- To review diagnostic strategies and management options for CMI specifically in older adults.
- To identify challenges and propose age-specific approaches for CMI evaluation and treatment.
Main Methods:
- Comprehensive literature review of diagnostic and management strategies for CMI in older adults.
- Analysis of existing data on challenges, preoperative optimization, and risk stratification.
Main Results:
- Older adults face unique diagnostic and therapeutic challenges for CMI.
- Thorough preoperative assessment, early optimization, and geriatric risk stratification are crucial.
- Limited data exist on long-term outcomes, nutrition, and quality of life post-intervention.
Conclusions:
- Age-specific approaches are necessary for evaluating and treating older adults with CMI.
- Further prospective studies are needed to address data gaps in long-term outcomes and quality of life.
- Integrating frailty and geriatric indices can improve therapeutic decision-making and patient outcomes.
Abstract:
Chronic mesenteric ischemia (CMI) is a rare, yet increasingly prevalent, condition, especially among older adults. Diagnosing CMI in older adults presents significant challenges. Along with the burden of comorbidities and the physiological changes associated with aging, timely intervention is often delayed, leading to poorer outcomes. Current diagnostic protocols and treatment guidelines do not address the unique challenges faced by this population. In this comprehensive review, the authors examined the existing literature on diagnostic strategies and management options for CMI in older adults. The importance of a thorough preoperative workup and early optimization to minimize perioperative stress, while considering nutritional and functional capabilities, is emphasized. Risk stratification models incorporating frailty and other geriatric-specific indices can inform therapeutic decisions and improve outcomes. Despite the increasing disease burden in this group, there are limited data on long-term outcomes, the impact of nutrition, and quality of life metrics after intervention. This emphasizes the necessity for more prospective studies to address these gaps and implement age-specific approaches for the evaluation and treatment of older adult patients with CMI.
Related Concept Videos
Chronic Pancreatitis II: Collaborative Care
Assessment:
Peripheral Artery Disease III: Interprofessional Care
Peripheral Artery Disease IV: Nursing Management
Atherosclerosis III: Management
Aneurysm III: Interprofessional Care
Ischemic Heart Disease: Overview
Atherosclerosis, the primary malefactor, orchestrates this dangerous condition. It manifests as the accumulation of fatty deposits, akin to insidious plaques, within arterial walls. As time elapses, these plaques metamorphose, hardening and...

