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Updated: Jan 18, 2026

3D Printing Model of a Patient's Specific Lumbar Vertebra
Published on: April 14, 2023
Assessing the ability of large language models to simplify lumbar spine imaging reports into patient-facing text: a
Rushmin Khazanchi1, Austin R Chen2, Parth Desai3
1Feinberg School of Medicine, Northwestern University, 676 N. St. Clair Street, Suite 1350, Chicago, IL, 60611, USA. rushmin.khazanchi@northwestern.edu.
Objective:
To assess the ability of large language models (LLMs) to accurately simplify lumbar spine magnetic resonance imaging (MRI) reports.
Materials And Methods:
Patients who underwent lumbar decompression and/or fusion surgery in 2022 at one tertiary academic medical center were queried using appropriate CPT codes. We then identified all patients with a preoperative ICD diagnosis of lumbar spondylolisthesis and extracted the latest preoperative spine MRI radiology report text. The GPT-4 API was deployed on deidentified reports with a prompt to produce translations and evaluated for accuracy and readability. An enhanced GPT prompt was constructed using high-scoring reports and evaluated on low-scoring reports.
Results:
Of 93 included reports, GPT effectively reduced the average reading level (11.47 versus 8.50, p < 0.001). While most reports had no accuracy issues, 34% of translations omitted at least one clinically relevant piece of information, while 6% produced a clinically significant inaccuracy in the translation. An enhanced prompt model using high scoring reports-maintained reading level while significantly improving omission rate (p < 0.0001). However, even in the enhanced prompt model, GPT made several errors regarding location of stenosis, description of prior spine surgery, and description of other spine pathologies.
Conclusion:
GPT-4 effectively simplifies the reading level of lumbar spine MRI reports. The model tends to omit key information in its translations, which can be mitigated with enhanced prompting. Further validation in the domain of spine radiology needs to be performed to facilitate clinical integration.
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