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Comparative efficacy of abdominal tuina and mosapride citrate in functional constipation: A clinical trial
Xiaoyu Shi1, Lingyun Shi1, Yukui Tian2
1Department of Spinal Surgery, The First Affiliated Hospital of Xinjiang Medical University, Urumqi, China.
Abstract:
Functional constipation (FC) is a prevalent gastrointestinal disorder that can significantly impact patients' quality of life. In this study, we aimed to evaluate the effectiveness and safety of "abdominal tuina" and oral mosapride citrate tablets in the treatment of FC. Ninety patients with FC were randomly assigned to receive either "abdominal tuina" treatment or oral mosapride citrate tablets. Symptom scores, quality of life assessments, physiological and biochemical indicators, and mental health parameters were monitored at various time points during the 90-day treatment period. Significant improvement in clinical symptom scores was observed in the experimental group by day 10, with sustained efficacy throughout the study. The experimental group demonstrated superior effectiveness and improvements in biochemical markers and mental health scores compared to the control group. No significant adverse reactions were reported in either group. The study findings suggest that "abdominal tuina" treatment and oral mosapride citrate tablets are equally effective in managing FC, with both interventions effectively reducing symptoms and enhancing quality of life without significant adverse effects. The maintenance of treatment effects at day 10 highlights the potential benefits of these therapies for FC patients.
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