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Updated: Jan 18, 2026

Retinal and Choroidal Thickness Changes in Populations with Helicobacter pylori Infection by Swept-Source Optical Coherence Tomography

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Published on: November 1, 2024

Structure-Function Associations of Choroidal Thickness With Retinal Sensitivity in Myopia.

Syna Sreng^1,2, Joey Chung¹, Angeline Toh¹

¹Singapore Eye Research Institute, Singapore National Eye Centre, Singapore, Singapore.

Investigative Ophthalmology & Visual Science

|September 9, 2025

Summary

This summary is machine-generated.

Choroidal thickness is linked to retinal sensitivity in myopic eyes, indicating a structure-function relationship. This study highlights the choroid

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In vivo Structural Assessments of Ocular Disease in Rodent Models using Optical Coherence Tomography

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Area of Science:

Ophthalmology
Retinal Imaging
Myopia Research

Background:

Myopia is associated with changes in ocular structures.
Understanding the relationship between choroidal thickness and retinal function is crucial for myopia management.

Purpose of the Study:

To investigate the focal relationship between choroidal thickness and retinal sensitivity in myopic eyes.
To explore structure-function associations in the context of myopia.

Main Methods:

Utilized swept-source optical coherence tomography (SS-OCT) for choroidal thickness measurement.
Employed microperimetry to assess retinal sensitivity at multiple locations.
Applied deep-learning for SS-OCT scan segmentation and analyzed focal structure-function associations.

Main Results:

Found significant correlations between choroidal thickness and retinal sensitivity in most retinal regions of myopic eyes.
Choroidal thickness was thinner in the nasal quadrant compared to other quadrants.
Focal structure-function models confirmed a significant effect of choroidal thickness on retinal sensitivity, adjusted for other factors.

Conclusions:

Demonstrated a significant structure-function relationship between choroidal thickness and retinal sensitivity in myopic eyes.
Suggests the choroid plays a role in visual function in myopia.
Further research is needed to validate these findings in diverse cohorts and longitudinal studies.