[Clinical and laboratory aspects of ultrasound treatment for chronic wounds]

To evaluate clinical and laboratory effectiveness of ultrasound treatment for purulent wounds.

The study enrolled 46 patients with purulent wounds divided into the main group (23 patients, ultrasonic treatment) and the control group (23 patients, traditional treatment). We assessed treatment effectiveness considering visual data, quality of granulation tissue, wound defect area and marginal epithelialization, complete blood count and C-reactive protein. Smear prints and acidity of wound discharge were analyzed.

In the main group, there was a faster completion of inflammatory phase and transition to proliferative one. This was accompanied by earlier granulations, reduced wound area and active marginal epithelialization with neutral pH of wound discharge. Neutrophil-lymphocytic and platelet-lymphocytic ratios significantly decreased after 3 days (2.56 and 118.23, respectively, p<0.05) compared to the control group. This decrease persisted at all stages of the study. After 10 days, NLR and TLR in the main group were 1.88 and 96.12, in the control group - 2.48 and 118.87, respectively. Serum CRP significantly decreased after 3 days in the main group (67.45 mg/l). After 10 days, CRP in the main group was 20.01 mg/l, in the control group - 56.87 mg/l (p<0.05).

Ultrasonic treatment of purulent wounds significantly improves cytological picture of wounds, accelerates wound debridement from devitalized tissues and epithelization, as well as reduces inflammation. These findings indicate higher effectiveness of treatment.