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Intracranial Rescue Stenting in Pediatric Focal Cerebral Arteriopathy.
Saujanya Rajbhandari1, Philipe Breiding1, Iciar Sanchez-Albisua2
1Department of Diagnostic and Interventional Neuroradiology, Inselspital, Bern University Hospital, University of Bern, Bern, Switzerland.
Clinical Neuroradiology
|September 9, 2025
Summary
Intracranial rescue stenting is a feasible treatment for pediatric acute ischemic stroke caused by focal cerebral arteriopathy. This approach led to neurological deficit resolution in all analyzed pediatric cases.
Area of Science:
- Neurology
- Pediatric Stroke
- Interventional Neuroradiology
Background:
- Pediatric acute ischemic stroke is a rare, severe condition often linked to vasculopathies.
- Endovascular intervention for pediatric focal cerebral arteriopathy is infrequently documented.
Purpose of the Study:
- To assess the feasibility of intracranial rescue stenting for pediatric focal cerebral arteriopathy with flow-limiting stenosis.
- To report on the management of acute ischemic stroke in children using this interventional technique.
Main Methods:
- A case report of a toddler with stroke due to focal cerebral arteriopathy treated with stenting.
- A systematic literature search (PubMed, Web of Science, Embase, Scopus) for pediatric stroke cases treated with intracranial stenting.
- Analysis of six eligible cases, extracting data on demographics, clinical presentation, etiology, stent details, and outcomes.
Main Results:
- Six pediatric cases of acute ischemic stroke treated with acute-stage intracranial stenting were analyzed.
- The supraclinoid internal carotid artery was the most common stenting site (4/6).
- Intracranial dissection was the leading cause of vessel occlusion (3/6), with all patients showing neurological deficit resolution within 6 months.
Conclusions:
- Off-label rescue stenting can be effective in pediatric acute ischemic stroke secondary to focal cerebral arteriopathy.
- Individualized, multidisciplinary management is crucial for this rare condition.
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