Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Acute Coronary Syndrome III: Diagnostic Studies01:30

Acute Coronary Syndrome III: Diagnostic Studies

190
Diagnosing acute coronary syndrome or ACS begins with a thorough patient history. Notable symptoms include central, crushing chest pain radiating to the left arm, neck, jaw, or back, along with shortness of breath, sweating (diaphoresis), nausea, vomiting, dizziness, and palpitations.It is crucial to note any history of cardiac illnesses and assess risk factors, including age, gender, smoking, hypertension, diabetes, hyperlipidemia, and a sedentary lifestyle.During physical examination, vital...
190
Acute Coronary Syndrome II: Pathophysiology and Clinical Manifestations01:19

Acute Coronary Syndrome II: Pathophysiology and Clinical Manifestations

323
The pathophysiology of Acute Coronary Syndrome [ACD] involves several key processes:The main underlying cause of ACD is atherosclerosis, a chronic inflammatory disease characterized by the buildup of lipid-laden plaques within the coronary arteries.As the atherosclerotic plaque grows in the coronary artery, it may become unstable due to the formation of a lipid-rich core and a thin fibrous cap. Inflammatory cells within the plaque, such as macrophages, secrete enzymes that degrade the...
323
Chronopharmacokinetics: Circadian Rhythms and Influence on Drug Response01:15

Chronopharmacokinetics: Circadian Rhythms and Influence on Drug Response

325
Circadian rhythms are cyclic changes that are crucial in plasma drug concentrations. Various standard circadian parameters, including core body temperature, heart rate, and other cardiovascular factors, directly impact disease states and the therapeutic response to drug therapy.
The time of drug administration is an important factor to consider, as it can influence the toxic dose of a drug. For example, a study conducted by Prins et al. in 1997 examined the effects of the timing of...
325
Acute Coronary Syndrome I: Introduction01:30

Acute Coronary Syndrome I: Introduction

690
Acute Coronary Syndrome (ACS) encompasses a spectrum of heart conditions caused by sudden obstruction of coronary arteries, typically resulting from the rupture of an atherosclerotic plaque and subsequent thrombus (blood clot) formation. This obstruction can lead to partial or complete blockage of blood flow, causing varying degrees of myocardial ischemia or infarction.ACS includes the following clinical entities:Unstable Angina (UA)Non-ST-Elevation Myocardial Infarction (NSTEMI)ST-Elevation...
690
Coronary Artery Disease III: Clinical Manifestations01:30

Coronary Artery Disease III: Clinical Manifestations

295
Coronary Artery Disease (CAD) is a primary health risk worldwide, leading to significant morbidity and mortality. The condition arises from the buildup of atherosclerotic plaques within the coronary arteries, resulting in diminished blood supply to the heart muscle.The clinical manifestations of CAD vary widely, from asymptomatic stages to severe, life-threatening conditions. Understanding these manifestations is crucial for early diagnosis and effective management.Angina Pectoris: The Warning...
295
Acute Coronary Syndrome IV: Interprofessional Care01:28

Acute Coronary Syndrome IV: Interprofessional Care

194
IntroductionThe management of Acute Coronary Syndrome (ACS) aims to minimize myocardial damage, preserve myocardial function, and prevent complications.Initial ManagementInpatient management involves continuous cardiac monitoring, preferably in an ICU, focusing on blood pressure, serum sodium, potassium, and creatinine levels, and urine output. Ongoing pharmacologic management is crucial for stabilizing the patient.Supplemental Oxygen: Administer supplemental oxygen if oxygen saturation is...
194

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Clinical Effectiveness of Sodium-Glucose Cotransporter-2 Inhibitors Among Older Patients Hospitalized for Heart Failure With Reduced Ejection Fraction.

Journal of the American Heart Association·2026
Same author

Trends in the Evaluation of Acute Chest Pain: An Analysis of the Chest Pain-MI National Cardiovascular Data Registry.

JACC. Cardiovascular imaging·2026
Same author

Audiovisual Augmentation of Electronic Consent to Improve Consent Rates and Comprehension: A Randomized Clinical Trial.

JAMA network open·2026
Same author

Aligning Coronary Stent Trial Enrollment With the U.S. Intended-Use Population: Implications of Site Selection.

Journal of the American College of Cardiology·2026
Same author

Contemporary Trends in Percutaneous Coronary Intervention at Facilities Without On-Site Cardiac Surgery: Insights From the National Cardiovascular Data Registry.

Journal of the American College of Cardiology·2026
Same author

The power, potential of real-world data in randomized controlled trials: proceedings from a multistakeholder think tank.

Trials·2026
Same journal

Notice of Retraction. Ren Y, et al. Personality Traits and Social Isolation in Older Adults. JAMA Netw Open. 2026;9(5):e269569.

JAMA network open·2026
Same journal

Error in Grant Number in Funding/Support Section.

JAMA network open·2026
Same journal

The Supplementary Role of Friends in Caregiving Networks.

JAMA network open·2026
Same journal

Urbanicity, Neighborhood Conditions, and Dementia Mortality.

JAMA network open·2026
Same journal

Equity and Cancer Survival Among Veterans Health Administration Patients: A Systematic Review and Meta-Analysis.

JAMA network open·2026
Same journal

Limbic System Microstructure in Neonates With Antenatal Opioid Exposure.

JAMA network open·2026
See all related articles

Related Experiment Video

Updated: Jan 6, 2026

A Research Method For Detecting Transient Myocardial Ischemia In Patients With Suspected Acute Coronary Syndrome Using Continuous ST-segment Analysis
18:11

A Research Method For Detecting Transient Myocardial Ischemia In Patients With Suspected Acute Coronary Syndrome Using Continuous ST-segment Analysis

Published on: December 28, 2012

24.7K

Daylight Savings Time and Acute Myocardial Infarction.

Jennifer A Rymer1,2, Shuang Li2, Karen Chiswell2

  • 1Division of Cardiology, Duke University Hospital, Durham, North Carolina.

JAMA Network Open
|September 9, 2025
PubMed
Summary
This summary is machine-generated.

Daylight saving time (DST) shifts were not associated with changes in acute myocardial infarction (AMI) incidence or in-hospital outcomes. This large study found no significant differences in AMI rates during DST weeks compared to the periods immediately before or after.

More Related Videos

Left Anterior Descending Coronary Artery Ligation for Ischemia-Reperfusion Research: Model Improvement via Technical Modifications and Quality Control
05:41

Left Anterior Descending Coronary Artery Ligation for Ischemia-Reperfusion Research: Model Improvement via Technical Modifications and Quality Control

Published on: December 16, 2022

4.2K
A Modified Simple Method for Induction of Myocardial Infarction in Mice
04:29

A Modified Simple Method for Induction of Myocardial Infarction in Mice

Published on: December 3, 2021

4.3K

Related Experiment Videos

Last Updated: Jan 6, 2026

A Research Method For Detecting Transient Myocardial Ischemia In Patients With Suspected Acute Coronary Syndrome Using Continuous ST-segment Analysis
18:11

A Research Method For Detecting Transient Myocardial Ischemia In Patients With Suspected Acute Coronary Syndrome Using Continuous ST-segment Analysis

Published on: December 28, 2012

24.7K
Left Anterior Descending Coronary Artery Ligation for Ischemia-Reperfusion Research: Model Improvement via Technical Modifications and Quality Control
05:41

Left Anterior Descending Coronary Artery Ligation for Ischemia-Reperfusion Research: Model Improvement via Technical Modifications and Quality Control

Published on: December 16, 2022

4.2K
A Modified Simple Method for Induction of Myocardial Infarction in Mice
04:29

A Modified Simple Method for Induction of Myocardial Infarction in Mice

Published on: December 3, 2021

4.3K

Area of Science:

  • Cardiology
  • Public Health
  • Chronobiology

Background:

  • Previous research suggested a potential link between daylight saving time (DST) transitions and an increased incidence of acute myocardial infarction (AMI).
  • Understanding this association is crucial for public health initiatives and patient care strategies.
  • The impact of both spring and fall DST shifts on cardiovascular events requires thorough investigation.

Purpose of the Study:

  • To investigate whether the incidence of acute myocardial infarction (AMI) is higher during weeks encompassing daylight saving time (DST) transitions.
  • To compare in-hospital clinical events, including mortality and stroke, between the week before DST and the week after DST.
  • To analyze the incidence of AMI and clinical outcomes during spring and fall DST periods.

Main Methods:

  • A cross-sectional study utilizing data from the Chest Pain MI Registry (2013-2022).
  • Inclusion of patients presenting 1 week before, during, or 1 week after DST (spring or fall).
  • Assessment of AMI incidence, in-hospital mortality, stroke, and clinical outcomes, with data analyzed from March 2024 to May 2025.

Main Results:

  • Analysis included 168,870 patients across 1124 hospitals.
  • No significant difference was found in the incidence of AMI during spring or fall DST weeks compared to the weeks immediately preceding or following.
  • Adjusted in-hospital outcomes also showed no significant differences between DST weeks and the surrounding periods.

Conclusions:

  • This study found no significant association between daylight saving time transitions and the incidence of acute myocardial infarction.
  • In-hospital clinical outcomes, including mortality and stroke, were not significantly different during DST weeks compared to non-DST weeks.
  • The findings suggest that DST shifts do not pose a significant risk for acute myocardial infarction or adverse in-hospital events.