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Resting Potential Decay

Resting Potential Decay

The resting membrane potential of a neuron (-70mV) is sustained due to the selective ion permeability of the membrane. At the resting potential, the membrane is slightly permeable to ions like sodium (Na+) and chloride (Cl−) and highly permeable to potassium ions (K+). Differences in the ions' concentration inside the cell compared to the outside are maintained by membrane transport proteins like channels and pumps.
At rest, the K+ is the main ion that moves across the membrane through...

Resting Potential Decay

Resting Potential Decay

The resting membrane potential of a neuron (-70mV) is sustained due to the selective ion permeability of the membrane. At the resting potential, the membrane is slightly permeable to ions like sodium (Na+) and chloride (Cl−) and highly permeable to potassium ions (K+). Differences in the ions' concentration inside the cell compared to the outside are maintained by membrane transport proteins like channels and pumps.
At rest, the K+ is the main ion that moves across the membrane through...

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Related Experiment Video

Updated: Jun 8, 2026

Acquisition of Resting-State Functional Magnetic Resonance Imaging Data in the Rat

Acquisition of Resting-State Functional Magnetic Resonance Imaging Data in the Rat

Published on: August 28, 2021

Age-Related Hearing Decline and Resting-State Networks.

Cassidy Teuscher Ellsworth^1,2, Lucas A Kortus², Joanne Vuong²

¹Department of Special Education and Communication Disorders, University of Nebraska-Lincoln.

American Journal of Audiology

|September 9, 2025

Summary

This summary is machine-generated.

Age-related hearing decline impacts brain functional networks, with older adults showing weaker connectivity. Preserving hearing sensitivity is linked to better local brain network efficiency and cognitive function.

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Area of Science:

Neuroscience
Audiology

Background:

Age-related hearing loss is a common sensory impairment.
Understanding its neural underpinnings is crucial for developing interventions.

Purpose of the Study:

To investigate the effects of age and hearing decline on brain functional networks.
To examine resting-state functional connectivity (RSFC) and network efficiency using graph theory.

Main Methods:

49 adults underwent pure-tone audiometry and resting-state functional magnetic resonance imaging (rs-fMRI).
RSFC and graph theory metrics were analyzed in auditory and attention networks.
Comparisons were made between age and hearing profile groups.

Main Results:

Older adults exhibited weaker RSFC in the salience network compared to middle-aged adults.
Individuals without hearing decline showed altered internetwork connectivity.
Better local efficiency in the salience network was observed in participants with normal hearing.

Conclusions:

Brain functional connectivity and network efficiency are significantly influenced by age and hearing thresholds.
rs-fMRI is valuable for studying the neural mechanisms of age-related hearing loss.