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Eye Drop Instillation Success and Hand Function in Adults with Glaucoma: A Pilot Study.
Madeline K Weber1, Gül G Kabil2, Leslie M Niziol3
1University of Michigan Medical School, Ann Arbor, Michigan.
Ophthalmology. Glaucoma
|September 9, 2025
Summary
Adults with glaucoma have hand function deficits but can still successfully instill eye drops. However, they are more likely to touch the bottle tip to their eye or skin, increasing contamination risk.
Area of Science:
- Ophthalmology
- Geriatrics
- Rehabilitation Medicine
Background:
- Glaucoma management often requires daily eye drop instillation.
- Hand function impairments are common in older adults, potentially affecting self-care tasks.
- The impact of glaucoma-related hand dysfunction on eye drop instillation success is not well understood.
Purpose of the Study:
- To compare hand function and eye drop instillation success between older adults with and without glaucoma.
- To identify specific hand function deficits in adults with glaucoma.
- To assess the relationship between hand function and successful eye drop administration.
Main Methods:
- Cross-sectional pilot study involving adults aged 65+.
- Participants included those with glaucoma using daily eye drops and controls without glaucoma.
- Hand function assessed using standardized tests (pinch/grip strength, dexterity, tactile sensitivity).
- Eye drop instillation success evaluated via videography, measuring successful drops, number dispensed, and bottle tip contact.
Main Results:
- No significant difference in overall successful eye drop instillation between groups.
- Participants with glaucoma showed significantly reduced pinch and grip strength, poorer dexterity (Grooved Pegboard Test, Arthritis Hand Function Tests), and reduced tactile acuity.
- Individuals with glaucoma had a higher incidence of bottle tip contact with the eye, eyelashes, or skin (49% vs. 28%).
Conclusions:
- Despite hand function deficits, older adults with glaucoma achieve comparable eye drop instillation success.
- Increased bottle tip contact in the glaucoma group suggests a higher risk of eye drop contamination.
- Hand function deficits may complicate eye drop instillation, necessitating strategies to mitigate risks.
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