Wearable bioelectronics for skin cancer management

Area of Science:

• Biomedical Engineering
• Oncology
• Materials Science

Background:

• Skin cancer, especially melanoma, presents significant diagnostic and therapeutic challenges due to high metastasis and mortality rates.
• Current diagnostic methods lack accuracy and reproducibility, while treatments face issues with toxicity and resistance.
• Wearable bioelectronics provide a promising avenue for continuous monitoring and targeted interventions.

Purpose of the Study:

• To review recent advancements in wearable bioelectronics for skin cancer management.
• To discuss wearable sensing and therapeutic platforms for early detection and treatment.
• To analyze key device attributes and future directions for clinical translation.

Main Methods:

• Systematic review of recent literature on wearable bioelectronics for skin cancer.
• Discussion of pathological mechanisms of skin cancer.
• Evaluation of wearable optical and electrochemical sensing technologies.
• Assessment of wearable therapeutic platforms (chemotherapy, photodynamic therapy, electrotherapy, immunotherapy) and combinatorial strategies.

Main Results:

• Wearable bioelectronics enhance diagnostic accuracy and treatment precision for skin cancer.
• Key device attributes like integration, mechanical properties, and biocompatibility are crucial for optimizing performance and patient compliance.
• Various wearable platforms show potential for non-invasive screening and targeted therapies.

Conclusions:

• Wearable bioelectronics offer innovative, patient-centered solutions for skin cancer diagnosis and treatment.
• Addressing technological bottlenecks and clinical translation barriers is essential for future applications in precision oncology.
• Interdisciplinary innovations in wearable devices can redefine skin cancer care, leading to safer and more effective outcomes.