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Updated: Jul 3, 2026

Preparation of Oligomeric β-amyloid1-42 and Induction of Synaptic Plasticity Impairment on Hippocampal Slices
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A synthetic nonapeptide, JAL-TA9, inhibits neuronal cytotoxicity caused by Aβ25-35 aggregation with proteolytic

Rina Nakamura1, Momoka Okada2, Asuka Takahashi3

  • 1O-Force Co., Ltd., 3454 Irino Kuroshio-cho, Hata-gun, Kochi 789-1931, Japan; Department of Pharmacology, Kochi Medical School, Kochi University, Kohasu, Oko-cho, Nankoku, Kochi 783-8505, Japan.

Neurobiology of Aging
|September 9, 2025
PubMed

Keywords:
AggregationAlzheimer’s diseaseAβ25–35Aβ42CatalytideHydrolase peptideJAL-TA9

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