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A Rare Orbital Trichilemmal Cyst: A Case Report
Agustina L Mena1, Margarita Isa1, Rodolfo L Vigo2
1Department of Ophthalmology.
Ophthalmic Plastic and Reconstructive Surgery
|September 9, 2025
Summary
This case report details a rare trichilemmal cyst found in the orbit of a 69-year-old female. The orbital tumor, confirmed by histology, is an unusual location for this type of hair follicle-derived cyst.
Area of Science:
- Ophthalmology
- Dermatopathology
- Neurosurgery
Background:
- Trichilemmal cysts are benign tumors typically arising from hair follicles.
- Orbital tumors are rare, and trichilemmal cysts in this location are exceptionally uncommon.
- Orbital proptosis and headache can indicate various orbital pathologies.
Purpose of the Study:
- To report a unique case of a trichilemmal cyst in the orbit.
- To highlight the diagnostic challenges and management of atypical orbital lesions.
- To contribute to the literature on rare orbital tumors.
Main Methods:
- Clinical presentation of a 69-year-old female with acute headache and unilateral proptosis.
- Computed Tomography (CT) scan revealing a cystic, hypodense orbital lesion with calcifications.
- Surgical excision and histopathological analysis of the orbital lesion.
Main Results:
- Histopathology confirmed the lesion as a trichilemmal tumor.
- The patient presented with symptoms of acute onset headache and left eye proptosis.
- The CT scan showed a well-defined, round, hypodense lesion with calcifications.
Conclusions:
- This is the first reported case of a trichilemmal cyst occurring in the orbit.
- Atypical presentations of common lesions should be considered in orbital tumor diagnosis.
- Surgical intervention and histological examination are crucial for definitive diagnosis.

