Advances in Infection Prevention for Pediatric and Neonatal Populations: Classification of Methods and the Emerging

Mitchell K Ng1, Michael A Mont2, Peter M Bonutti3

  • 1Orthopaedic Surgery, Maimonides Medical Center, Brooklyn, USA.

Cureus
|September 10, 2025
PubMed

Insights

Healthcare-associated infections (HAIs) pose risks to vulnerable pediatric patients. Emerging technologies like UV-C disinfection offer advanced, chemical-free solutions to improve infection prevention and patient safety.

Area of Science:

  • Pediatric Infection Control
  • Healthcare Epidemiology
  • Disinfection Technologies

Background:

  • Healthcare-associated infections (HAIs) present significant risks to pediatric and neonatal patients due to immature immune systems.
  • Conventional infection prevention methods (chemical, physical, procedural) have limitations including human error, toxicity, and antimicrobial resistance.
  • There is a need for advanced, reliable strategies to mitigate HAIs in pediatric settings.

Purpose of the Study:

  • To systematically review and classify infection prevention methods for pediatric patients.
  • To evaluate the strengths and limitations of traditional and emerging disinfection technologies.
  • To highlight the potential of next-generation UV-C disinfection systems in pediatric infection control.

Main Methods:

  • Systematic classification of infection prevention strategies into chemical, physical, procedural, and emerging technology categories.
  • Review of current literature on disinfection technologies, focusing on Ultraviolet-C (UV-C) systems.
  • Analysis of UVCeed, a novel UV-C device, for its application in pediatric settings.

Main Results:

  • Traditional methods for HAI prevention are limited by factors such as human error and antimicrobial resistance.
  • Ultraviolet-C (UV-C) disinfection systems represent a promising advancement in pathogen control.
  • UVCeed offers rapid, chemical-free decontamination with reduced reliance on user compliance.

Conclusions:

  • Advanced disinfection technologies, particularly UV-C, can significantly enhance pediatric infection control protocols.
  • UVCeed technology addresses critical gaps in conventional methods, offering a safer and more effective decontamination solution.
  • Integrating innovative technologies is crucial for comprehensive protection of pediatric patients against HAIs.

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