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Updated: Jan 18, 2026

Droplet Barcoding-Based Single Cell Transcriptomics of Adult Mammalian Tissues
Published on: January 10, 2019
Bioconductor: Planning a third decade of comprehensive support for genomic data science
1Channing Division of Network Medicine, Mass General Brigham, 181 Longwood Avenue, Boston, MA 02115, USA.
Abstract:
This opinion piece discusses the Bioconductor project for open-source bioinformatics and the engineering concepts underlying its effectiveness to date. Since the inception of Bioconductor in 2002 with 15 software packages devoted to analysis of DNA microarrays, it has grown into an ecosystem of ∼3,000 packages contributed by more than 1,000 developers. Aspects of the history and commitments are reviewed here to contribute to thinking about the design and orchestration of future open-source software projects.
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