Clinical Outcomes of a Multicenter Study Following Implantation of an Isofocal Optic IOL with Double C-Loop Haptics

To report clinical outcomes in patients implanted with an isofocal optic-design intraocular lens (IOL) with double C-loop haptics following cataract surgery.

This was a multicentre-prospective-study involving 108 eyes (54 subjects) implanted with the Isopure Serenity (BVI, Inc). IOL. At least 3 months after the surgery, the following parameters were analysed: refraction, monocular uncorrected distance visual acuity (UDVA), corrected distance visual acuity (CDVA), uncorrected intermediate visual acuity (UIVA) and distance corrected-intermediate visual acuity (DCIVA) both at 80 and 66 cm, uncorrected near visual acuity (UNVA), and distance corrected near visual acuity (DCNVA) at 40 cm. In addition, the binocular defocus curve was measured.

79.63% and 98.15% of eyes were within ±0.50D and ±1.00D of the target spherical equivalent, respectively. 68.41% and 98.15% of eyes had a UDVA and CDVA of 20/20 or better, respectively, with 88.89% and 99.07% achieving 20/25 or better, respectively (the mean values for UDVA and CDVA were 0.02±0.11 and -0.04±0.05 logMAR, respectively). 77.14% and 39.39% of eyes achieved a DCIVA of 20/32 or better at 80 cm and 66 cm, respectively, and 90% and 72.73% achieved a DCIVA of 20/40 or better at 80 and 66 cm, respectively (the mean values for DCIVA were 0.19±0.10 and 0.28±0.11 logMAR, 80 cm and at 66 cm, respectively). 25% and 15.15% of eyes had a UNVA and DCNVA of 20/32 or better, respectively, with 39.81% and 31.82% achieving a UNVA and DCNVA of 20/40 or better, respectively (mean values for UNVA and DCNVA were 0.37±0.15 logMAR and 0.40±0.13 logMAR, respectively). The defocus curve showed a peak of visual acuity at far distance with a depth-of-focus value of about 1.75D.

Patients implanted with the new Isopure Serenity IOL with double C-loop haptics showed good visual performance at far distance with functional intermediate vision and accurate refractive outcomes.