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The oxidative rearrangements in bacterial aromatic polyketide biosynthesis

Fangwen Jiao1,2,3, Shuai Li1, Hongzhi Qiao2,4

  • 1Department of Pathogen Biology, School of Medicine, Nanjing University of Chinese Medicine, Nanjing 210023, China.

Natural Product Reports
|September 10, 2025
PubMed
Summary

This review explores how bacterial enzymes use redox chemistry to create complex aromatic polyketides. It highlights unique oxidative rearrangements crucial for natural product biosynthesis and drug development.

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