Children Treated for Slow-flow Vascular Malformations: Overall Description and Focus on Complications Such as

Stephanie Bredy1, Emilie Coronas1, Caroline Degrugillier-Chopinet2

  • 1CHU Lille, Urgences Pédiatriques & Maladies Infectieuses, Hôpital R. Salengro, Lille, France.

Acta Dermato-Venereologica
|September 10, 2025
PubMed

Insights

Cellulitis is rare in children with slow-flow vascular malformations (SFVMs), but can become recurrent. Young children with specific SFVM types and certain characteristics face higher risks, potentially needing antibiotic prophylaxis.

Area of Science:

  • Pediatric vascular anomalies
  • Infectious disease epidemiology
  • Dermatology

Background:

  • Slow-flow vascular malformations (SFVMs) can present with complications.
  • Recurring cellulitis is a known complication in some SFVM patients.
  • Understanding cellulitis risk factors in pediatric SFVMs is crucial for management.

Purpose of the Study:

  • To describe the characteristics of SFVMs in a pediatric cohort.
  • To determine the incidence and frequency of cellulitis episodes in children with SFVMs.
  • To identify factors associated with the occurrence of cellulitis in this population.

Main Methods:

  • Retrospective, longitudinal, single-center study.
  • Inclusion of pediatric patients with SFVMs managed between 1994 and 2020.
  • Data collection via standardized questionnaire; descriptive and analytical statistics used.

Main Results:

  • 133 children with SFVMs were analyzed (median age 72 months, 53% girls).
  • Venous malformations were most common (81%).
  • 7% of patients experienced cellulitis, with recurrence common; risk factors included younger age, lymphatic/syndromic SFVMs, large size, skin fold involvement, and lack of long-term treatment.

Conclusions:

  • Cellulitis is infrequent in pediatric SFVM patients but often recurrent.
  • Identified risk factors suggest specific patient subgroups may benefit from prophylactic antibiotics.
  • Further research into preventative strategies for recurrent cellulitis in pediatric SFVMs is warranted.

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