Related Experiment Video
Updated: Aug 16, 2026
Assessing Early Stage Open-Angle Glaucoma in Patients by Isolated-Check Visual Evoked Potential
Published on: May 25, 2020
Comparison of 10-2 Visual Field Using Melbourne Rapid Fields Online Perimetry and Humphrey Field Analyzer
Kae Sugihara1, Yu Xiang George Kong2,3, Mitsuto Hosokawa1
1Department of Ophthalmology, Kurashiki Medical Center, Kurashiki, Okayama, Japan.
Purpose:
Melbourne rapid fields (MRF) online perimetry is web-based software that allows white-on-white threshold perimetry using any computer. This study assesses the perimetric outcomes of MRF10-2 protocol via laptop computer in comparison to Humphrey field analyzer (HFA).
Methods:
This prospective and cross-sectional study included 91 eyes from 91 Japanese glaucoma patients. MRF10-2 visual field (VF) results were compared to HFA10-2 the Swedish Interactive Thresholding Algorithm (SITA)-Standard, including mean deviation (MD), pattern deviation (PD), and reliability indexes. To assess test-retest reliability, patients completed two MRF assessments.
Results:
MRF demonstrated high level of agreement with HFA in evaluating MD (intraclass correlation coefficient [ICC] = 0.97 [95% confidence interval {CI}, 0.96-0.98]) and pattern standard deviation (PSD; ICC = 0.94 [95% CI, 0.92-0.96]). Bland-Altman analysis revealed a mean bias of -1.31 decibels (dB) (95% limits of agreement [LoA] = -7.21 dB, 4.59 dB) for MD and 0.71 dB (LoA = -3.55 dB, 4.97 dB) for PSD. It also demonstrated good MRF repeatability with a mean bias of 0.39 dB (LoA = -2.34 dB, 3.00 dB) for MD and -0.21 dB (LoA = -2.36 dB, 1.94 dB) for PSD. False-positives and -negatives were not statistically different between the two devices. MRF test time was significantly shorter than HFA (P < 0.001).
Conclusions:
MRF10-2 online perimetry offers portable approach for central VF assessment, but its measurements are not directly interchangeable with HFA and may exhibit higher variability, warranting caution in clinical interpretation.
Translational Relevance:
The novel protocol of portable online perimetry approach will assess central VF defects when standard equipment is unavailable.
