Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Search research articles

Related Experiment Videos

Benign hereditary chorea--response to steroids.

R O Robinson, C E Thornett

Developmental Medicine and Child Neurology

|December 1, 1985

Summary

This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

Effect of lamotrigine on cognition in children with epilepsy.

Neurology·2006

Same author

Factors influencing PCR detection of viruses in cerebrospinal fluid of patients with suspected CNS infections.

Journal of neurology, neurosurgery, and psychiatry·2004

Same author

Lower limb extensor moments in children with spastic diplegic cerebral palsy.

Gait & posture·2004

Same author

The impact of PET scanning on management of paediatric oncology patients.

European journal of nuclear medicine and molecular imaging·2004

Same author

Infantile Parkinsonism-dystonia and elevated dopamine metabolites in CSF.

Neurology·2004

Same author

Accurate measurement of muscle belly length in the motion analysis laboratory: potential for the assessment of contracture.

Gait & posture·2003

Benign hereditary chorea in a child resolved with systemic steroids, a novel finding. This suggests steroids may modulate neurotransmitter function to improve movement disorders.

Area of Science:

Neurology
Genetics
Pharmacology

Background:

Benign hereditary chorea is a rare genetic movement disorder.
Characterized by involuntary, purposeless, jerky movements.
Typically presents in childhood and persists into adulthood.

Observation:

A pediatric case of benign hereditary chorea is presented.
The patient exhibited significant improvement in choreiform movements.
This remission was observed following treatment with systemic steroids.

Findings:

The movement disorder demonstrated a positive response to systemic corticosteroid therapy.
This represents a previously undescribed therapeutic effect for this condition.
The mechanism is hypothesized to involve the modulation of neurotransmitter systems.

Related Experiment Videos

Implications:

Systemic steroids may offer a potential treatment avenue for benign hereditary chorea.
Further research is warranted to elucidate the neurobiological mechanisms involved.
This finding could inform future therapeutic strategies for similar movement disorders.