Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

UV–Vis Spectroscopy: Molecular Electronic Transitions01:16

UV–Vis Spectroscopy: Molecular Electronic Transitions

In Ultraviolet–Visible (UV–Vis) spectroscopy, the absorption of electromagnetic radiation is used to probe the electronic structure of molecules. This technique provides insights into molecular electronic transitions, particularly the movement of electrons between different molecular orbitals. Radiation is absorbed if the energy of the electromagnetic radiation passing through the molecule is precisely equal to the energy difference between the excited and ground states. During this process,...
Electron Microscope Tomography and Single-particle Reconstruction01:07

Electron Microscope Tomography and Single-particle Reconstruction

Transmission electron microscopy (TEM) can be used to determine the 3D structure of biological samples with the help of techniques such as electron microscope tomography and single-particle reconstruction. While single-particle reconstruction can examine macromolecules and macromolecular complexes in vitro conditions only, tomography permits the study of cell components or small cells in vivo.
Electron Tomography
Electron tomography can be performed either in TEM or STEM (scanning transmission...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Excited-state orbital angular momentum enables all-optical molecular spin coherence.

Chemical science·2026
Same author

Molecular Qubits for Anion Sensing by Tuning Electron Spin Relaxation via Axial Ligand Field.

Angewandte Chemie (International ed. in English)·2026
Same author

Mapping Molecular/Nanocrystal Orientation with Nano-FTIR.

The journal of physical chemistry letters·2026
Same author

Experimental Quantification of Spin-Phonon Coupling in Molecular Qubits Using Inelastic Neutron Scattering.

Journal of the American Chemical Society·2026
Same author

Ultrafast Population and Structural Dynamics of a Ni-Bipyridine Photoredox Catalyst Reveal a Significant Deactivation Pathway.

The journal of physical chemistry letters·2026
Same author

Spin Dynamics and Ionic Strength Sensitivity in Nitroxide-Doped Micelles.

The journal of physical chemistry letters·2025

Related Experiment Video

Updated: May 11, 2026

Rejection of Fluorescence Background in Resonance and Spontaneous Raman Microspectroscopy
15:04

Rejection of Fluorescence Background in Resonance and Spontaneous Raman Microspectroscopy

Published on: May 18, 2011

13.5K

Prolonging All-Optical Molecular Electron Spin Coherence in the Tissue Transparency Window.

Erica Sutcliffe1, Jacob O Rothbaum1, Jonathan P Aalto1

  • 1Division of Chemistry and Chemical Engineering, Arthur Amos Noyes Laboratory of Chemical Physics, California Institute of Technology, Pasadena, California 91125, United States.

Journal of the American Chemical Society
|September 10, 2025
PubMed
Summary

Researchers developed an all-optical method to measure electron spin coherence in paramagnetic molecules, enhancing quantum sensing. Immobilizing molecules significantly increased coherence lifetime and magnetic field sensitivity.

More Related Videos

Microfluidic Imaging Flow Cytometry by Asymmetric-detection Time-stretch Optical Microscopy ATOM
07:19

Microfluidic Imaging Flow Cytometry by Asymmetric-detection Time-stretch Optical Microscopy ATOM

Published on: June 28, 2017

10.7K
Transient Optical Clearing Using Absorbing Molecules for Ex Vivo and In Vivo Imaging
07:15

Transient Optical Clearing Using Absorbing Molecules for Ex Vivo and In Vivo Imaging

Published on: July 11, 2025

2.2K

Related Experiment Videos

Last Updated: May 11, 2026

Rejection of Fluorescence Background in Resonance and Spontaneous Raman Microspectroscopy
15:04

Rejection of Fluorescence Background in Resonance and Spontaneous Raman Microspectroscopy

Published on: May 18, 2011

13.5K
Microfluidic Imaging Flow Cytometry by Asymmetric-detection Time-stretch Optical Microscopy ATOM
07:19

Microfluidic Imaging Flow Cytometry by Asymmetric-detection Time-stretch Optical Microscopy ATOM

Published on: June 28, 2017

10.7K
Transient Optical Clearing Using Absorbing Molecules for Ex Vivo and In Vivo Imaging
07:15

Transient Optical Clearing Using Absorbing Molecules for Ex Vivo and In Vivo Imaging

Published on: July 11, 2025

2.2K

Area of Science:

  • Quantum sensing
  • Molecular spin dynamics
  • Spectroscopy

Background:

  • Paramagnetic molecules offer potential for microscopic quantum sensing.
  • Achieving high-resolution, all-optical coherence measurements at room temperature is challenging.
  • Electron spin decoherence limits quantum sensing applications.

Purpose of the Study:

  • To develop an all-optical method for measuring electron spin decoherence time (T2*) in paramagnetic molecules.
  • To investigate decoherence mechanisms and enhance coherence lifetimes.
  • To enable ultrafast molecular electron spin coherence imaging in biological systems.

Main Methods:

  • Picosecond time-resolved Faraday ellipticity/rotation (TRFE/R) measurements at room temperature.
  • Investigated decoherence in [IrBr6]2- in solution and immobilized in polymer films.
  • Tuned ligand-to-metal charge transfer (LMCT) states for spin initialization and readout.

Main Results:

  • Decoherence was sensitive to solution viscosity, indicating molecular tumbling as a key mechanism.
  • Immobilization in polymer films increased coherence lifetime by an order of magnitude.
  • Achieved significantly greater magnetic field sensitivity in immobilized samples.

Conclusions:

  • Molecular immobilization is a viable strategy to enhance electron spin coherence lifetimes.
  • TRFE/R spectroscopy is a powerful tool for ultrafast molecular spin coherence studies.
  • This technique opens possibilities for all-optical, high-resolution imaging in biological tissues.