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Updated: Jan 18, 2026

Multimodal Protocol for Assessing Metacognition and Self-Regulation in Adults with Learning Difficulties
Published on: September 27, 2020
Edwards syndrome: Neurocognitive and linguistic profile, diagnosis, overlaps and treatment
Dimitra V Katsarou1, Alexandros Argyriadis2, Maria Sofologi3
1UNIVERSITY OF THE AEGEAN, MITILINI, GREECE.
Objective:
Aim: To provide a comprehensive understanding of the profound developmental and medical challenges associated with this condition..
Patients And Methods:
Materials and Methods: Τhis study employed a narrative review methodology, drawing upon a wide range of peer-reviewed scientific literature, clinical guidelines, and case studies. The reviewed materials were selected based on their relevance to the neurocognitive, linguistic, diagnostic, and therapeutic aspects of Edwards syndrome. Databases such as PubMed, Scopus, and Google Scholar were used, with key terms including "Edwards syndrome," "trisomy 18," "developmental delays," "prenatal diagnosis," and "palliative care." Comparative analysis was conducted to explore clinical overlaps with related syndromes such as trisomy 13 and Turner syndrome.
Conclusion:
Conclusions: Edwards syndrome presents significant challenges, requiring early diagnosis and multidisciplinary care to improve quality of life. Comprehensive understanding and tailored interventions can foster better outcomes and enhance family support systems.
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