Evaluating the Long-term Effects of Microfocused Ultrasound on Facial Tightening Using Quantitative Instruments:...

Area of Science:

• Aesthetic Medicine
• Dermatology
• Medical Technology

Background:

• Microfocused ultrasound (MFU) is a non-invasive facial rejuvenation technique.
• Limited quantitative data exists on the long-term effects of MFU.
• This study evaluates the long-term efficacy and safety of MFU for facial rejuvenation.

Purpose of the Study:

• To assess the 12-month efficacy and safety of MFU for facial rejuvenation.
• To analyze the impact of MFU on facial morphology and skin function.
• To evaluate patient satisfaction following MFU treatment.

Main Methods:

• Prospective clinical study with 28 female subjects (33-55 years).
• Single MFU treatment with assessments at multiple follow-up points up to 12 months.
• Objective measurements included facial volume, nasolabial fold morphology, skin parameters, and aesthetic scores.

Main Results:

• Peak efficacy at 3 months, with sustained benefits through 12 months.
• Significant volume reduction in facial and submental regions, with superior durability in the submental area.
• Improved nasolabial fold depth and skin collagen intensity; enhanced skin hydration and reduced TEWL.
• High patient satisfaction (89.2% willing to retreat) and mild, transient adverse events (erythema, edema).

Conclusions:

• MFU facial rejuvenation exhibits a time-dependent efficacy profile with sustained results.
• Anatomical variations and nasolabial fold morphology influence treatment outcomes.
• MFU offers significant rejuvenation with minimal downtime, high satisfaction, and an excellent safety profile.