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Causal Effects of Immune Cell Populations on Cognitive Performance: A Mendelian Randomization Study

Jingfeng Fu1,2, Minmin Yang1, Qingteng Zheng1

  • 1School of Pharmacy and Medical Technology, Putian University, Putian, China.

Brain and Behavior
|September 11, 2025
PubMed
Summary

Seven immune cell types causally influence cognitive function, with specific B cell and T cell subsets showing significant associations. These findings highlight immune pathways that may regulate cognitive performance and offer targets for interventions.

Keywords:
Mendelian randomizationcognitive performancegenome‐wide association studyimmune cells

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