Related Experiment Video
Updated: May 13, 2026

10:35
Precision Measurements and Parametric Models of Vertebral Endplates
Published on: September 17, 2019
6.8K
Identification of Johnson-Cook Model Parameters for Human Cortical Bone Using Inverse Finite Element Method to
Syed Naveed Ul Meiraj1,2, Pandithevan Ponnusamy1,2, Roger Narayan3,4
1Department of Mechanical Engineering, Indian Institute of Information Technology, Design and Manufacturing, Kancheepuram, Chennai 600127, Tamilnadu, India.
Journal of Biomechanical Engineering
|September 11, 2025
Summary
This study identifies Johnson-Cook model parameters for human cortical bone, enabling accurate simulations for surgical planning. These findings advance in silico testing for medical procedures.
Area of Science:
- Biomechanics
- Computational Material Science
- Orthopedic Surgery
Background:
- Constitutive models (CMs) predict material stress-strain relationships via computer simulation.
- Existing CMs like Johnson-Cook are based on animal or surrogate bone data, limiting human bone application.
- Accurate human bone models are crucial for simulating surgical procedures and developing implants.
Purpose of the Study:
- To determine Johnson-Cook model parameters specifically for human cortical bone.
- To validate the model's accuracy through tensile test simulations and experimental data comparison.
- To demonstrate the model's utility in simulating orthopedic surgical operations.
Main Methods:
- Utilized the inverse finite element method (FEM) to identify Johnson-Cook model parameters.
- Employed the Levenberg-Marquardt optimization algorithm (LMOA) to refine parameter values.
- Conducted tensile test simulations across a range of strain rates (0.00001-1/s).
Main Results:
- Successfully identified Johnson-Cook model parameters for human cortical bone.
- Simulations demonstrated strong agreement with experimental tensile test results.
- A case study on orthogonal bone cutting validated the model's applicability.
Conclusions:
- The derived Johnson-Cook model parameters provide a reliable representation of human cortical bone behavior.
- This research enables accurate in silico simulation of complex surgical operations.
- Facilitates virtual surgical rehearsal and practice, reducing the need for physical experimentation.

