Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

Hydrogel degradation products as immunomodulatory cues in neural injury: mechanisms and implications for neural repair.

Journal of materials chemistry. B·2026

Same author

Co-culturing hiPSC-cardiomyocytes and cardiac fibroblasts enhances engineered heart tissue structure and function.

Stem cells translational medicine·2026

Same author

Precision Cardiogenomics in Athletes.

International journal of molecular sciences·2026

Same author

Nanostructure and Crystallinity Govern the Rheology and Printability of Cellulose-Based Bioinks.

ACS biomaterials science & engineering·2026

Same author

Engineered multicomponent bioink enables neuronal maturation and activity in brain-like tissue models.

Trends in biotechnology·2026

Same author

New Insights in Exercise for Arrhythmogenic Cardiomyopathy: A Narrative Review.

CJC open·2026

Search research articles

Related Experiment Video

Updated: Jan 18, 2026

Transplantation of a 3D Bioprinted Patch in a Murine Model of Myocardial Infarction

Transplantation of a 3D Bioprinted Patch in a Murine Model of Myocardial Infarction

Published on: September 26, 2020

Building the framework for bioprinted human heart tissue: recent developments and future prospects.

Victor A da Silva¹, Man Chi Leung^2,3, McGregor Clayton^1,4,5

¹Department of Mechanical Engineering, University of Victoria, Victoria, BC, Canada.

Regenerative Medicine

|September 11, 2025

Summary

Cardiac bioprinting offers potential for patient-specific grafts and drug testing, but faces challenges in precision, bioinks, and vascularization. Overcoming these hurdles requires integrated strategies for clinical impact.

Keywords:

Cardiac bioprinting bioink development drug screening platforms functional maturation induced pluripotent stem cells scalable cell manufacturing tissue engineering vascularization strategies

More Related Videos

Creation of Cardiac Tissue Exhibiting Mechanical Integration of Spheroids Using 3D Bioprinting

Creation of Cardiac Tissue Exhibiting Mechanical Integration of Spheroids Using 3D Bioprinting

Published on: July 2, 2017

3D Human Myocardial Tissue Generation Using Melt Electrospinning Writing of Polycaprolactone Scaffolds and hiPSC-Derived Cardiac Cells

3D Human Myocardial Tissue Generation Using Melt Electrospinning Writing of Polycaprolactone Scaffolds and hiPSC-Derived Cardiac Cells

Published on: March 28, 2025

Related Experiment Videos

Last Updated: Jan 18, 2026

Transplantation of a 3D Bioprinted Patch in a Murine Model of Myocardial Infarction

Transplantation of a 3D Bioprinted Patch in a Murine Model of Myocardial Infarction

Published on: September 26, 2020

Creation of Cardiac Tissue Exhibiting Mechanical Integration of Spheroids Using 3D Bioprinting

Creation of Cardiac Tissue Exhibiting Mechanical Integration of Spheroids Using 3D Bioprinting

Published on: July 2, 2017

3D Human Myocardial Tissue Generation Using Melt Electrospinning Writing of Polycaprolactone Scaffolds and hiPSC-Derived Cardiac Cells

3D Human Myocardial Tissue Generation Using Melt Electrospinning Writing of Polycaprolactone Scaffolds and hiPSC-Derived Cardiac Cells

Published on: March 28, 2025

Area of Science:

Biotechnology
Regenerative Medicine
Tissue Engineering

Background:

Cardiac bioprinting aims to create patient-specific cardiac grafts and drug-testing platforms.
Significant challenges impede the clinical translation of current cardiac bioprinting technologies.

Purpose of the Study:

To review key barriers in cardiac bioprinting.
To discuss recent advances and their applications in drug discovery and graft fabrication.
To highlight future directions for advancing cardiac bioprinting.

Main Methods:

Review of current literature on cardiac bioprinting challenges and advances.
Analysis of limitations including bioprinting precision, bioink development, vascularization, functional maturation, and cell sourcing.
Discussion of recent innovations like multimodal printing, hybrid bioinks, and perfusable constructs.

Main Results:

Key barriers identified: precision, bioinks, vascularization, maturation, cell sourcing/processing.
Advances in multimodal printing, hybrid bioinks, and perfusable constructs show promise.
Drug screening requires targeted maturation, while grafts need greater complexity and immune compatibility.

Conclusions:

Addressing challenges in precision, vascularization, and immune compatibility is crucial.
Multidisciplinary strategies are essential for advancing cardiac bioprinting.
Cardiac bioprinting holds potential for drug discovery and regenerative therapies.