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Corneal Donor Tissue Preparation for Endothelial Keratoplasty
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Intracorneal hypopyon within a DSAEK graft.

Angelica Piccini1, Jia Yin1, Levi N Kanu1

  • 1From the Department of Ophthalmology, Massachusetts Eye and Ear Infirmary, Harvard Medical School, Boston, Massachusetts (Piccini, Yin, Kanu); Schepens Eye Research Institute, Massachusetts Eye and Ear Infirmary, Boston, Massachusetts (Yin, Kanu); Cooper Medical School of Rowan University, Camden, New Jersey (Piccini).

JCRS Online Case Reports
|September 11, 2025
PubMed
Summary
This summary is machine-generated.

Intracorneal hypopyon, an unusual collection of inflammatory cells within the cornea, can occur after Descemet-stripping automated endothelial keratoplasty (DSAEK). Anterior segment optical coherence tomography (AS-OCT) is key to differentiating it from persistent infiltrates.

Area of Science:

  • Ophthalmology
  • Corneal Surgery
  • Infectious Keratitis

Background:

  • Intracorneal hypopyon is a rare condition involving inflammatory cell accumulation within the cornea.

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  • Descemet-stripping automated endothelial keratoplasty (DSAEK) is a surgical procedure for corneal diseases.
  • This case highlights an unusual presentation of intracorneal hypopyon within a DSAEK graft.