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Updated: Jan 18, 2026

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Structure-guided deep learning for back acupoint localization via bone-measuring constraints.

Yulong Wang1, Tian Lan2, Wenjian Dou3

  • 1School of Artificial Intelligence and Information Technology, Nanjing University of Chinese Medicine, Nanjing, China.

Frontiers in Physiology
|September 11, 2025
PubMed
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This study presents an AI framework for precise acupoint localization in Traditional Chinese Medicine (TCM), integrating bone measurement principles with deep learning for accurate, real-time identification of back acupoints.

Area of Science:

  • Medical Imaging
  • Artificial Intelligence
  • Traditional Chinese Medicine

Background:

  • Accurate acupoint localization is essential for effective acupuncture and Traditional Chinese Medicine (TCM) therapies.
  • Current methods may lack precision across diverse body types and conditions.

Purpose of the Study:

  • To develop and validate a novel automated framework for recognizing back acupoints using deep learning.
  • To integrate traditional TCM bone-measuring principles with advanced AI for enhanced accuracy.

Main Methods:

  • The framework utilizes an HRFormer backbone with a Structure-Guided Keypoint Estimation Module (SG-KEM).
  • A structure-constrained loss function ensures anatomically consistent predictions within a standardized spatial coordinate system.
  • The model was trained and evaluated on 430 high-resolution back images with 19 annotated acupoints.
Keywords:
HRFormeracupoint localizationanatomical landmark detectionartificial intelligencebone-measuring methodmedical imaging

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Main Results:

  • The framework achieved a normalized mean error (NME) of 0.6% and a failure rate (FR@1 cm) of 1.2%.
  • Real-time performance was demonstrated at 18 frames per second with high precision (93.8%) and AUC (0.97).
  • The SG-KEM module and structure-constrained loss significantly reduced mean error, showing robustness in obese individuals and under varying illumination.

Conclusions:

  • The developed framework offers a clinically viable and computationally efficient solution for intelligent acupoint localization.
  • This AI-assisted approach supports accurate diagnosis and personalized treatment strategies in modern TCM.
  • The study highlights the potential of integrating traditional principles with deep learning for advancing TCM healthcare.