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Updated: Jan 18, 2026

Large-Scale Multi-Omics Genome-Wide Association Studies Mo-GWAS: Guidelines for Sample Preparation and Normalization
Published on: July 27, 2021
Omics landscapes in molecular mechanisms with Amomum tsaoko as an example
Dengke Fu1,2, Yuanzhong Wang1, Jinyu Zhang1
1Medicinal Plants Research Institute, Yunnan Academy of Agricultural Sciences, Kunming 650205, China.
Abstract:
To improve the quality and efficiency of cultivating Amomum tsaoko (AT), a non-model plant, it is crucial to understand the intrinsic molecular mechanisms underlying its growth. This review summarizes the significance of multi-omics in the study of plant molecular mechanisms and illustrates how multi-omics technology can solve the practical problems of non-model plants using AT as an example. In this review, we argue that nonlinear dimensionality reduction is more suitable for data organization in multi-omics because it is compatible with the nonlinear relationship between the components of systems biology. Subsequently, researchers have verified the strong vitality of multi-omics from three perspectives: the natural communication, breeding, and shade tolerance mechanisms of AT. Finally, we summarized some of the current commonly used plant genome databases and analyzed their utility for such research. We believe that our study makes a significant contribution to the literature because this review summarizes the multi-omics research process in detail, from data processing to application to the use of public databases, and illustrates the potential for the application of multi-omics with the example of a non-model plant, AT.
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