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Updated: Jul 24, 2026

Registered Bioimaging of Nanomaterials for Diagnostic and Therapeutic Monitoring
Published on: December 9, 2010
Exploring plant-derived carbon dots: Dual-functional nanomaterials for endodontic infections and enhanced bio-imaging
Malavika Pradeep1, Anju Cecil1, Nidhita Suresh1
1Department of Periodontics, Saveetha Dental College and Hospitals Saveetha Institute of Medical and Technical Sciences(SIMATS), Saveetha University, Chennai, 600077, India.
Background:
Endodontic infections are a major problem of public health, which requires new therapeutic and diagnostic approaches. Carbon dots (CDs) derived from natural sources have great potential as nanomaterials because of their exceptional properties, including biocompatibility and photoluminescence.
Aim:
An investigation into the therapeutic possibilities of carbon dots derived from long pepper leaves(LCDs) for treating endodontic infections and parallel bio-imaging functionality forms the core research objective.
Method:
LCDs through a hydrothermal process and checked their properties with FTIR, SEM-EDX, and fluorescence equipment. They tested the cells' acceptance of LCDs along with their resistance to bacteria and ability to enter cells using fibroblast growth tests, the Streptococcus mutans bacteria test, and microscope imaging.
Results:
LCDs promoted better fibroblast development and endodontic infections healing above previous treatment standards. Biopsy tests show that LCD material kills Streptococcus mutans bacteria easily while also readily up taking cells for potential for Bio-imaging.
Conclusion:
The study demonstrates that LCD types serve both as a medication for endodontic infections repair and a tool for living tissue observation. we have found a novel approach that will bring new possibilities to both managing endodontic infections and medical imaging techniques.
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