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Application of Deep Learning-Based Medical Image Segmentation via Orbital Computed Tomography
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Open-Source Periorbital Segmentation Dataset for Ophthalmic Applications.

George R Nahass1,2, Emma Koehler1, Nicholas Tomaras1

  • 1Department of Ophthalmology, University of Illinois Chicago College of Medicine, Chicago, Illinois.

Ophthalmology Science
|September 11, 2025
PubMed
Summary
This summary is machine-generated.

A new dataset for oculoplastic segmentation and periorbital distance prediction has been created. This dataset demonstrates high annotation reliability and enables the development of advanced deep learning models for craniofacial applications.

Keywords:
Artificial intelligenceComputer VisionDatasetsOculoplastic surgeryOpen source

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Area of Science:

  • Ophthalmology
  • Computer Vision
  • Medical Imaging

Background:

  • Accurate segmentation of periorbital structures is crucial for oculoplastic and craniofacial surgery.
  • Existing datasets lack specificity for oculoplastic segmentation tasks.
  • Development of robust deep learning models requires high-quality, specialized datasets.

Purpose of the Study:

  • To create and validate a novel dataset for oculoplastic segmentation.
  • To enable periorbital distance prediction using deep learning models.
  • To facilitate advancements in craniofacial and oculoplastic surgical planning.

Main Methods:

  • Utilized images from two open-source datasets, cropped to focus on the eye region.
  • Involved segmentation of key periorbital structures (iris, sclera, lid, caruncle, brow) by five trained annotators.
  • Performed rigorous inter- and intragrader reliability analyses using Dice scores.
  • Trained three DeepLabV3 segmentation models to demonstrate dataset utility.

Main Results:

  • Annotated a total of 2842 images with high inter- and intragrader reliability (average Dice scores of 0.82 and 0.81, respectively).
  • Achieved strong performance with segmentation models, with Dice scores up to 0.90 for models trained on combined datasets.
  • Demonstrated the dataset's effectiveness in training deep learning models for segmentation tasks.

Conclusions:

  • Developed a unique, publicly available dataset for oculoplastic and craniofacial segmentation.
  • The dataset supports the rapid development of clinically relevant segmentation networks for periorbital distance prediction.
  • Provided open-source toolkits and model weights to foster community-driven innovation in the field.