Related Experiment Video
Updated: Jan 18, 2026
Multiplex Therapeutic Drug Monitoring by Isotope-dilution HPLC-MS/MS of Antibiotics in Critical Illnesses
Published on: August 30, 2018
Enhancing antimicrobial stewardship program: impact of clinical pharmacist-driven feedback in the absence of
Anup R Warrier1, Nalluri Tejaswini2, Hafeedha Kallarakkal3
1Department of Infectious Diseases, Aster Medcity, Kochi, Kerala, India.
Objective:
To evaluate the impact of clinical pharmacist-driven feedback on Antimicrobial Stewardship Program (AMSP) in the absence of infectious disease physicians across three different geographic locations.
Design:
Multicenter quasi-experimental study.
Setting:
Three private tertiary referral centers in different geographical locations in India.
Participants:
All consecutive prescriptions with restricted antibiotics for inpatients during the study period.
Intervention:
This study was conducted over 15 months from June 2022 to May 2023. The impact of mentoring clinical pharmacists by infectious disease physicians, enhancing their communication abilities for providing proactive feedback, and the impact on prescription practice were measured in terms of new prescriptions of restricted antibiotics, compliance to clinical pharmacist advice, and the duration of restricted antibiotic therapy usage, measured in terms of days of therapy (DOT) of restricted antibiotics. Gross mortality was reviewed as a balancing measure, and dose/dosing errors were considered as a secondary outcome. Data were captured in Microsoft Excel and analyzed using the SPSS software.
Results:
Clinical pharmacist-led antimicrobial stewardship interventions were found to have a significant impact on decreasing antibiotic prescriptions, increasing healthcare organization policy compliance, and decreasing DOT for restricted antibiotics. Culture sampling, acceptance of antimicrobial stewardship advice, dosing errors, or mortality rates were not statistically significantly related to the other study parameters.
Conclusion:
Clinical pharmacist-driven AMSP can be effectively implemented irrespective of the cultural and geographical setting due to their ability to improve prescription practices.
More Related Videos
09:26Antibiotic Efficacy Testing in an Ex vivo Model of Pseudomonas aeruginosa and Staphylococcus aureus Biofilms in the Cystic Fibrosis Lung
Published on: January 22, 2021
07:16Development of a Polymicrobial Colony Biofilm Model to Test Antimicrobials in Cystic Fibrosis
Published on: September 20, 2024
Related Concept Videos
01:28Antimicrobial Effectiveness
01:19Pharmacovigilance
This process, termed pharmacovigilance, aims to detect, evaluate, and minimize harmful effects related to medication use. The data collection for pharmacovigilance depends on spontaneous reporting systems, where healthcare professionals or patients voluntarily report suspected ADRs.
In some cases, there...
01:23Types of Biopharmaceutical Studies: Controlled and Non-Controlled Approaches
Non-controlled studies, commonly employed for initial exploration, lack a control group, rendering them susceptible to biases and external influences. In contrast,...
01:22Healthcare Associated Infections II: Preventive Measures
The best practices for preventing healthcare-associated infections include hand hygiene, patient risk...
01:22Pharmaceutical Alternatives: Stability-Related Therapeutic Nonequivalence
00:46Feedback Inhibition