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Updated: Jan 18, 2026

Catalytic Scavenging of Plant Reactive Oxygen Species In Vivo by Anionic Cerium Oxide Nanoparticles
Published on: August 26, 2018
Uniformly distributed Cu2O/Cu nanoparticles supported on graphite phase carbon: An enhanced peroxidase mimic for
Jiahui Huang1, Siyi Wei2, Maopu Tu3
1Cancer Research Center & Jiangxi Engineering Research Center for Translational Cancer Technology, Jiangxi University of Chinese Medicine & Jiangxi Province Key Laboratory for Diagnosis, Treatment, and Rehabilitation of Cancer in Chinese Medicine, Nanchang, Jiangxi, 330004, China.
Abstract:
The measurement of total antioxidant capacity (TAC) is vital for evaluating the nutrient content of foods and beverages. The development of novel mimetic enzyme materials with high catalytic activity has led to the creation of highly sensitive methods for TAC assessment. In this study, we introduce a simple and efficient approach for preparing uniformly distributed Cu2O/Cu nanoparticles supported on graphite-phase carbon (g-C@Cu2O/Cu NPs). These g-C@Cu2O/Cu NPs demonstrate excellent peroxidase-like (POD-like) enzymatic activity and exhibit a strong binding affinity for TMB, with a Km value of 0.24 mM. A colorimetric analytical platform for TAC assessment was developed, utilizing g-C@Cu2O/Cu NPs, TMB, and H2O2 as the chromogenic system. The method achieved a limit of detection for ascorbic acid as low as 0.15 μM, with a linear range from 0.5 to 100 μM. Furthermore, this method was successfully applied to evaluate TAC in real samples, highlighting its significant potential for food nutritional analysis.

