Related Experiment Video
Updated: Jul 27, 2026

Purification of a High Molecular Mass Protein in Streptococcus mutans
Published on: September 14, 2019
Removal of penicillin G from contaminated milk by ultrafiltration
Abstract:
Penicillin G purposedly added to whole raw milk at concentrations from .05 to .20 IU/ml was removed to undetectable levels by a combination of ultrafiltrations and permeate washes. After penicillin removal, whole milk 3:1 vol/vol concentrated retentates were reconstituted to milk with antibiotic-free permeate with little change in composition and with very good to excellent flavor. Washing 3:1 vol/vol concentrated retentates from penicillin-contaminated milks with water also removed penicillin to an undetectable level but changed the composition of product, which displayed a flat flavor.
Related Concept Videos
Drug Elimination by Renal Route: Tubular Secretion
Extracorporeal Removal of Drugs: Hemoperfusion and Hemofiltration
Physical Methods for Controlling Microbial Growth: Radiation and Filtration
Production of Antibiotics
Downstream Processing

